Nonparametric regression, often called smoothing, is a widely used data analysis method. The use of a smoother requires the choice of a smoothing parameter that by balancing Ž delity and roughness controls how much smoothing is done. Two popular selection criteria for choosing the smoothing parameter are Cp and generalized maximum likelihood (GML). Each of these has its own problems. For Cp , t...

Gastric MALT lymphoma (GML) can be induced by Helicobacter pylori infection in BALB/c mice thymectomised at day 3 post-birth (d3Tx). This represented a unique opportunity to investigate the inflammatory process involved in the recruitment, proliferation and structuration of lymphoid infiltrates in the gastric mucosa of mice developing GML. Complementary molecular and proteomic approaches demons...

In den letzten Jahren ist eine Trendwende im Bereich der Geodatenmodellierung in Gange. Wurden früher die meisten konzeptionellen Geodatenmodelle anhand von ER-Diagrammen semantisch modelliert und im Anschluss im Rahmen des Implementierungsprozesses in ein logisches Datenbankschema übergeführt, so setzt sich in den letzten Jahren immer mehr der Trend zur modellgetriebenen Softwareentwicklung (M...

In our aim to modernize geographical legacy data from the German office of geographical survey with XML languages, we first modeled the data in GML, a standard language for geography markup. The resulting model has then been used as a template for a JAVA application that assembles the necessary information from the legacy data and writes it into a GML document. During the second part of our wor...

This article considers spline smoothing of variance functions. We focus on selection of smoothing parameters and develop three direct data-driven methods: unbiased risk (UBR), generalized approximate cross validation (GACV) and generalized maximum likelihood (GML). In addition to guaranteed convergence, simulations show that these direct methods perform better than existing indirect UBR, genera...

GML, the G>raph Modelling Language, is our proposal for a portable file format for graphs. GML's key features are portability, simple syntax, extensibility and flexibility. A GML file consists of a hierarchical key-value lists. Graphs can be annotated with arbitrary data structures. The idea for a common file format was born at the GD'95; this proposal is the outcome of many discussions. GML is...

GML is becoming the world standard for the exchange of spatial data. Since the latest release of the GML standard (GML3) there is support for the modelling and exchange of topological data in GML. In this paper we take a closer look at the topological model in GML3 and discuss two issues that arose when we tried to encode the Dutch Cadastral model in GML. The first issue that arose was that the...

A few mixed ligand transition metal carbodithioate complexes of the general formula [M(4-MPipzcdt)x(phen)y]Y (M = Mn(II), Co(II), Zn(II); 4-MPipzcdt = 4-methylpiperazine-1-carbodithioate; phen = 1,10-phenanthroline; x = 1 and y = 2 when Y = Cl; x = 2 and y = 1 when Y = nil) were synthesized and screened for their antimicrobial activity against Candida albicans, Escherichia coli, Pseudomonas aer...

nowadays, standardized metadata for geospatial data is a key in sharing and finding information on the web and crucial in building geospatial data infrastructure (gdi). the main objective of this paper was to develop a web-based metadata dissemination system for in-situ sensors based on, most importantly, interoperable, standard and open technologies introduced by open gis consortium (ogc), nam...

The objective of this paper is to address two issues of current Internet Geographic Information Systems (GIS) programs – interoperability and graphic image output issues – using standard-based technologies, specifically, the Geography Markup Language (GML), Scalable Vector Graphics (SVG) and the OpenGIS Web Feature Service (WFS) Implementation Specifications developed by the OpenGIS Consortium ...