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This paper presents a comprehensive review of how recent advances in flow injection-capillary electrophoresis (FI-CE) technology have led to enhanced separation capabilities of a wide range of analytes in such areas as biological, environmental, food, medical and pharmaceutical analysis. Significant developments in design, detection methodology and applications made in the last five years are r...

An extremely rapid on-chip separation of DNA from its single-base substituted mutant is described. By using affinity capillary electrophoresis (ACE) in a poly(dimethylsiloxane) (PDMS)-glass hybrid microdevice, we achieved the separation within 5 s.

Pulmonary oedema due to pulmonary capillary leak syndrome during the use of cyclosporin, particularly when given intravenously, has been reported in some patients after bone marrow, liver, and renal transplantation [1-4]. Suggested explanations for this effect have been a local high concentration of the drug in the pulmonary vessels when infused through a central line [3], or the solvent polyox...

Idiopathic systemic capillary leak syndrome (ISCLS) is a rare condition that is characterized by unexplained episodic capillary hyperpermeability due to a shift of fluid and protein from the intravascular to the interstitial space. This results in diffuse general swelling, fetal hypovolemic shock, hypoalbuminemia, and hemoconcentration. Although ISCLS rarely induces cerebral infarction, we expe...

Percutaneous closure of a prosthetic paravalvular leak (PVL) is a challenging procedure. Operators must use devices constructed for other applications. We present the use of a device which is specifically designed for PVL closure. To the best of our knowledge, there is no publication in MEDLINE reporting the use of the device.

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