The title compound, C18H20N2O3S, exists as the phenol-imine form in the crystal and there are bifurcated intra-molecular O-H⋯(N/O) hydrogen bonds present. The conformation about the C=N bond is anti (1E); the C=N imine bond length is 1.287 (4) Å and the C=N-C angle is 122.5 (3)°. In the tetrahydrothienopyridine moiety, the six-membered ring has a flattened-boat conformation. In the crystal, mol...

Synthesis of a 9-membered azaenediyne has been achieved for the first time via intramolecular N-alkylation; the importance of proximity of the reacting centres via cobalt carbonyl complexation of the acetylenic moiety and not the activation of propargylic carbon has been demonstrated.

In the title compound, C(22)H(22)O(3), the dihedral angle between the naphthalene ring system and the benzene ring is 79.95 (5)°. The bridging carbonyl C-C(=O)-C group makes dihedral angles of 24.21 (7) and 82.43 (8)°, respectively, with the naphthalene ring system and the benzene ring. In the crystal, weak inter-molecular C-H⋯O inter-actions link mol-ecules into chains parallel to the c axis.

A series of benzaldehyde substituted phenyl carbonyl hydrazones has been synthesized and their formylation has been carried out by using Vilsmeier-Haack reaction. All the hydrazones and their formyl derivatives were screened for antibacterial activity.

A BODIPY-based fluorescent probe bearing a pyridyl hydrazone motif responds selectively to Au(III) ions through an irreversible C=N bond hydrolysis reaction.

In the title compound, C(23)H(17)ClN(4)O(2), the amino H atom forms an intra-molecular hydrogen bond to the exocyclic carbonyl O atom as well as to the O atom of the benzoyl group.

In the title compound, C(16)H(17)FN(2)O(4)·H(2)O, the dihedral angle between the heterocyclic ring and the benzene ring is 5.77 (9)°, that between the heterocycle and the ethoxy-carbonyl plane is 15.5 (1)°, and that between the heterocyclic ring and the cyclopropane ring is 67.75 (13)°. In the crystal structure, mol-ecules are linked into a ribbon-like structure along the c axis by N-H⋯O and O-...

Synlett 2002, No. 11, Print: 29 1

Weak inter- and intra- molecular C(δ+)F(δ-)···C(δ+)=O(δ-) interactions were theoretically evaluated in 4 different sets of compounds at different theoretical levels. Intermolecular CH3F···C=O interactions were stabilizing by about 1 kcal mol(-1) for various carbonyl containing functional groups. Intramolecular CF···C=O interactions were also detected in aliphatic and fluorinated cyclohexane car...

Transient carbonyl nitrenes RC(O)N, formed during thermal- or photoinduced decomposition of carbonyl azides RC(O)N3, are highly liable to the Curtius rearrangement, producing isocyanates RNCO in almost quantitative yield. Contrary to common belief, we found a thermally persistent triplet carbonyl nitrene, FC(O)N, that can be produced by flash pyrolysis of FC(O)N3 in 49% yield. The computed CBS-...