Macrae, I. C. (Cornell University, Ithaca, N.Y.), and M. Alexander. Metabolism of phenoxyalkyl carboxylic acids by a Flavobacterium species. J. Bacteriol. 86:1231-1235. 1963.-A Flavobacterium sp. isolated from soil and grown in media containing 4-(2,4-dichlorophenoxy) butyric acid metabolized omega-linked 2,4-dichlorophenoxyalkyl carboxylic acids in the series from 3-(2,4-dichlorophenoxy)propio...

Cellulolytic enzymes consist of a catalytic domain, a linking peptide, and a binding domain. The paper describes research on carboxylic acids that have potential as catalytic domains for constructing organic macromolecules for use in cellulose hydrolysis that mimic the action of enzymes. The tested domains consist of the series of mono-, di-, and tricarboxylic acids with a range of pK(a)'s. Thi...

The mixed anhydrides with N-acyl carbamic acid (IV) were prepared by the reaction of carboxylic acids (Ill) with N-chlorocarbonyl lactams (Ila) or sec. amides (lib). Decarboxylation of IV yielded N-acyl lactams (VI), while symmetrical anhydrides (VII) were obtained by the side reaction of IV with carboxylic acids (III). Aminolysis of IV yielded carboxylic acid amides (IX) in high yield and puri...