INTRODUCTION Results on the evolution of the clinical status of patients undergoing cardiac resynchronization therapy with a defibrillator after automatic optimization of their cardiac resynchronization therapy are scarce. We observed a rapid and important change in the clinical status of our non-responding patient following activation of a sensor capable of weekly atrioventricular and interven...

chronisation and implantable cardioverter defibrillation in advanced chronic heart failure: the Miracle ICD trial. JAMA 2003;289:2685–2694. 25. van Veldhuisen DJ, Maass AH, Priori SG, Stolt P, van Gelder IC, Dickstein K, Swedberg K. Implementation of device therapy (cardiac resynchronization therapy and implantable cardioverter defibrillator) for patients with heart failure in Europe: changes f...

Despite an array of treatment modalities, the overall prognosis for patients with severe heart failure remains bleak. Biventricular pacing, or cardiac resynchronization therapy, is gaining increasing acceptance as a compelling treatment for those individuals with advanced heart failure (New York Heart Association functional class III or IV). This article provides a brief description of the atri...

chronization therapy. Cardiol Res Pract 2010;22:568918. 32. Porapakkham P, Porapakkham P, Zimmet H, Billah B, Krum H. B-type natriuretic peptide-guided heart failure therapy: a meta-analysis. Arch Intern Med 2010;170: 507–14. 33. Felker GM, Thompson RE, Hare JM, Hruban RH, Clemetson DE, Howard DL et al. Underlying causes and long-term survival in patients with initially unexplained cardiomyopat...

Cardiac resynchronization therapy (CRT) has been shown to consistently improve cardiac performance and exercise capacity, leading to reversal of cardiac remodeling and improvement in survival in patients with advanced heart failure and a significant ventricular conduction delay. The strategy of CRT for the treatment of advanced heart failure was secured in 2005 by the landmark Cardiac Resynchro...

Background—We hypothesized that combined assessment of factors that are associated with favorable reverse remodeling after cardiac resynchronization-defibrillator therapy (CRT-D) can be used to predict clinical response to the device. Methods and Results—The study population comprised 1761 patients enrolled in the Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchroniza...

BACKGROUND Cardiac resynchronization therapy has emerged as an important therapy for advanced systolic heart failure. Among available cardiac resynchronization therapy pacing modes that restore ventricular synchrony, it is uncertain whether simultaneous biventricular (BiV), sequential BiV, or left ventricular (LV) pacing is superior. The Device Evaluation of CONTAK RENEWAL 2 and EASYTRAK 2: Ass...

Ventricle to ventricle (VV) delay optimization can provide an additional benefit to cardiac resynchronization therapy, but the methods currently used for optimization are time consuming and operator-dependent. We present two cases of VV-delay optimization with the use of a new intracardiac electrogram method. (Cardiol J 2007; 14: 305-310).

Daubert JP, Eldar M, Gold MR, Goldberger JJ, Goldenberg I, Lichstein E, Pitschner H, Rashtian M, Solomon S, Viskin S, Wang P, Moss AJ. Effectiveness of cardiac resynchronization therapy by QRS morphology in the Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy (MADIT-CRT). Circulation 2011;123:1061–1072. 14. Fang F, Chan JY, Yip GW, Xie JM, Zhang Q, Fung J...

A randomized, controlled trial of baroreflex activation therapy (BAT) in patients with heart failure and reduced ejection fraction demonstrated that BAT was safe significantly improved patient-centered symptomatic outcomes, increasing exercise capacity, improving quality life , decreasing n-terminal pro B-type natriuretic peptide (NT-proBNP), functional class. approved by the FDA for improvemen...