Affiliations: Dept of General Practice, Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Dept of Clinical Pharmacy & Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Dept of Experimental and Clinical Medicine, University of Florence, Florence,...

aim : this study evaluated the association between serum endothelin- 1 level and symptoms, clinical examination, laboratory and cardio-respiratory parameters, in patients with cirrhosis compared to controls. background : cirrhosis is associated with significant portal, pulmonary and systemic vascular abnormities. recent studies have suggested that endothelin -1 may have a significant role in th...

Morbidity and mortality in cardio-vascular diseases can be described as an ongoing epidemic, although a very protracted one, lasting more than 100 years. Cardiovascular diseases still top mortality rates in the world today, accounting for about 30% of all deaths around the globe. But it is in the industrialized world that cardio-vascular diseases dominate, although differences are great among v...

RATIONALE During the last decennium a more focused attention has been directed to the presence of chronic inflammation in cardiovascular diseases (CVD), but mainly to the high impact that this one has in generating and fastening the atherosclerotic process. OBJECTIVE To highlight the causal relationship between periodontal diseases (PD) and CVD. One of the most important chronic inflammations...

chronic  obstructive  pulmonary  disease (copd)  and  asthma  are  major  public  health problems, which seems to have close association with psychiatric disorders. the present study was conducted to compare the psychological status between asthmatic and copd patients and clarify the relationship with severity of pulmonary obstruction. this cross-sectional study was planned to compare the psych...

BACKGROUND Several epidemiological studies have found U- or J-shaped relationships between alcohol intake and cardiovascular conditions. The influence of heavy drinking is, however, sparsely studied. The objective of the present study was to examine whether alcohol addicts have higher incidence rates of cardio- and cerebrovascular diseases than the population in general. METHODS The cohort co...