BACKGROUND The genotypic diversity and cariogenicity of C. albicans from the dental plaque of children are poorly understood. This study aimed to explore the genotypic diversity and cariogenicity of C. albicans from children with early childhood caries and caries-free children. METHODS Dental plaque samples from 238 children with early childhood caries and from 125 caries-free children were c...

Despite the fact that it is preventable, dental caries remains a global public health problem—even with fluoride intervention—and it is the most common chronic disease on the planet. Moreover, researchers have already shown for some years that caries is a disease continuum that at the early stages is reversible, yet many Ministries of Health and dental professionals misunderstand this. We belie...

BACKGROUND Dental caries is a chronic disease among children and there is need for studies assessing the caries risk factors using saliva. This study aimed to evaluate the association of salivary soluble CD14 and dental caries in young children. MATERIAL AND METHODS A cross-sectional study was done among 300, 3-6 year old school children of Udupi district. A total of 40 children who were cari...

BACKGROUND Little research has been carried out on whether the parental stress affects children's oral health in general and dental caries in particular. This study aimed to investigate the association between parental stress and early childhood caries (ECC). METHODS A cross-sectional study was designed that included 250 children of 4-6 year-old; 127 ones attended the pediatric department of ...

OBJECTIVE The aim of this formative international collaborative research on childhood dental caries was to undertake an initial investigation comparing the dental plaque of young children from diverse ethnic and socioeconomic backgrounds with and without dental caries. BASIC RESEARCH DESIGN The following four null hypotheses were investigated. There were no differences in numbers of individua...

Introduction Minimal attention has been given to the role of salivary microelements, the importance they have in reducing the intensity of caries, and the effect of caries prophylaxes. Aim This research aimed to determine the concentration and quantity of Zn and its impact on the prevention and the reduction of the intensity of caries in schoolchildren aged 12-13 years with permanent dentitio...

BACKGROUND The ecological plaque hypothesis for the etiopathogenesis of caries implies a microbial shift towards a more aciduric dental plaque microbiota, due to a frequent carbohydrate intake. Acid tolerance has been suggested as an important property of the caries-associated bacteria and several in vitro studies with mixed cultures indicated that a low pH rather than the carbohydrate availabi...

We conducted a parallel group randomized controlled trial of children initially aged 2 to 3 y who were caries free, to prevent the children becoming caries active over the subsequent 36 mo. The setting was 22 dental practices in Northern Ireland, and children were randomly assigned by a clinical trials unit (CTU) (using computer-generated random numbers, with allocation concealed from the denta...