Variants in Atherosclerosis, Obesity, and Bone Traits Since learning of the Letter to the Editor by Lyons1 we sequenced the 5-lipoxygenase (5-LO) gene in strains 129/SvJ, CAST/EiJ, and a congenic strain carrying a CAST/Ei allele. The sequences are in agreement with those indicated by Dr Lyons. CAST is a “wild-derived” strain, and we can only speculate that the stock we sequenced may not have be...

Five single-nucleotide polymorphisms (SNPs) located in the calpain 1, (mu/I) large subunit (CAPN1), calpastatin (CAST), and cathepsin D (CTSD) genes were analyzed in a large sample of Piemontese cattle. The aim of this study was to evaluate allele and genotype frequencies of these SNPs and to investigate associations of CAPN1, CAST, and CTSD gene variants with meat quality traits. Minor allele ...

We demonstrated previously that food intake traits map to a quantitative trait locus (QTL) on proximal chromosome 17, which encompasses Glp1r (glucagon-like peptide 1 receptor), encoding an important modulator of gastric emptying. We then confirmed this QTL in a B6.CAST-17 congenic strain that consumed 27% more carbohydrate and 17% more total calories, yet similar fat calories, per body weight ...

Introduction: The purpose of beading & boxing of an impression is to obtain an accurate cast with proper border & base thickness for fabrication of restorations. Beading is the protection of the formed border thickness of the final impressions & Boxing of an impression is building up vertical walls around it. Aim: The purpose of this hybrid technique of beading and boxing is to produce a smooth...

background: creating a socket with proper fit is an important factor to ensure the comfort and control of prosthetic devices. several techniques are commonly used to cast transtibial stumps but their effect on stump shape deformation is not well understood. this study compares the dimensions, circumferences and volumes of the positive casts and also the socket comfort between two casting method...

background and aims. current chemical methods may not efficiently disinfect dental stone casts. the aim of this study was to investigate if microwave irradiation is effective for disinfection of stone casts. materials and methods. in this laboratory study, three groups (n = 162) of prepared spherical stone beads as carriers with a diameter of 10 mm were inoculated by separately soaking in three...