نتایج جستجو برای: ccnu
تعداد نتایج: 395 فیلتر نتایج به سال:
The spin labeled nitrosoureas 7a-e and 12 were synthesized and evaluated in vivo for their anticancer activities against the murine lymphocytic leukemia P388. Compounds 7a-c, 7e and 12 possessed activities ranging from 31 to 542 percent increase in life span (%ILS), whereas compound 7d was marginal (%ILS = 21). All CD2F1 male mice treated with the most active compounds (7a and 12) at 35 mg/kg f...
PURPOSE To determine the event-free survival (EFS) and overall survival of children with average-risk medulloblastoma and treated with reduced-dose craniospinal radiotherapy (CSRT) and one of two postradiotherapy chemotherapies. METHODS Four hundred twenty-one patients between 3 years and 21 years of age with nondisseminated medulloblastoma (MB) were prospectively randomly assigned to treatme...
BACKGROUND Grade 2 gliomas occur most commonly in young adults and cause progressive neurologic deterioration and premature death. Early results of this trial showed that treatment with procarbazine, lomustine (also called CCNU), and vincristine after radiation therapy at the time of initial diagnosis resulted in longer progression-free survival, but not overall survival, than radiation therapy...
*From the Pathology and Cardiology Branches, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md. Reprint requests: Dr. Roberts, National Institutes of Health, Bldg bA, Room 3E30, Bethesda 20205 before death), the patient noted a “lump” in her groin, and excision again disclosed melanoma. The results of a chest roentgeno gram (Fig 1), gallium scan, and cardiop...
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