نتایج جستجو برای: cd16

تعداد نتایج: 2438  

Journal: :The Journal of Experimental Medicine 1985
L L Lanier T J Kipps J H Phillips

A subset of peripheral blood T lymphocytes coexpressing CD3 and IgG Fc receptors (FcR) (CD16/Leu-11 antigen) have been identified, isolated, and functionally characterized. The CD3+, CD16+ cells were established in short-term culture using growth medium containing interleukin 2 (IL-2). Both the freshly isolated cells and the cultured cell line stably expressed the CD3+, CD16+ phenotype. Further...

2013
Dionna W. Williams Tina M. Calderon Lillie Lopez Loreto Carvallo-Torres Peter J. Gaskill Eliseo A. Eugenin Susan Morgello Joan W. Berman

As HIV infected individuals live longer, the prevalence of HIV associated neurocognitive disorders is increasing, despite successful antiretroviral therapy. CD14(+)CD16(+) monocytes are critical to the neuropathogenesis of HIV as they promote viral seeding of the brain and establish neuroinflammation. The mechanisms by which HIV infected and uninfected monocytes cross the blood brain barrier an...

Journal: :The Journal of Experimental Medicine 2002
Gwendalyn J. Randolph Guzman Sanchez-Schmitz Ronald M. Liebman Knut Schäkel

Much remains to be learned about the physiologic events that promote monocytes to become lymph-homing dendritic cells (DCs). In a model of transendothelial trafficking, some monocytes become DCs in response to endogenous signals. These DCs migrate across endothelium in the ablumenal-to-lumenal direction (reverse transmigration), reminiscent of the migration into lymphatic vessels. Here we show ...

Journal: :Annals of the Rheumatic Diseases 2023

Background Cellular immunity of Behçet’s Disease (BD) remains poorly understood. Previous work has provided clues pointing to most innate and adaptive immune cell types in BD, but strong signals from non-immunogenetic studies are rare often inconclusive. Objectives Here we aimed identify BD/HD discriminant single profiles semi-biased targeted approaches determine their significance at a BD rele...

2015
Marcin Moniuszko

__________________________________________________________________________________________ Monocytes are comprised of three phenotypically and functionally distinct subsets: classical CD14++CD16-, intermediate CD14++CD16+ and non-classical CD14+CD16++ cells that can play differential roles in regulation of both systemic and local inflammatory processes. In addition, these monocyte subsets repre...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شهید چمران اهواز 1388

به نظر می رسد که ورزش با شدت متوسط سیستم ایمنی بدن را تحریک می کند، اما شواهد خوبی نیز وجود دارد که نشان می دهد تمرین شدید می تواند باعث تضعیف سیستم ایمنی شود. هدف تحقیق حاضر، مقایسه اثر یک جلسه تمرین فزاینده درمانده ساز هوازی توسط دست و پا بر پاسخ سلول های nk) cd16، cd56، cd16/56)و t) cd4، cd8، cd4/cd8) سیستم ایمنی دانشجویان پسر رشته تربیت بدنی دانشگاه شهید چمران اهواز بود. بدین منظور 20 آزمود...

Journal: :Cancer research 1989
A C Ochoa D E Hasz R Rezonzew P M Anderson F H Bach

Peripheral blood lymphocytes cultured in recombinant interleukin 2 during 3 to 5 days (short-term cultures) develop the ability to lyse natural killer-resistant tumor lines and fresh tumor cells, i.e., express lymphokine-activated killer (LAK) function. Phenotypic analysis has shown these cells to be natural killer cells, i.e., CD16+ and/or Leu 19+ cells. CD3+,CD16- T-cells, instead, develop ve...

2011
Gabriella Passacquale Padman Vamadevan Luis Pereira Colleen Hamid Valerie Corrigall Albert Ferro

BACKGROUND Activated platelets exert a pro-inflammatory action that can be largely ascribed to their ability to interact with leukocytes and modulate their activity. We hypothesized that platelet activation and consequent formation of monocyte-platelet aggregates (MPA) induces a pro-inflammatory phenotype in circulating monocytes. METHODOLOGY/PRINCIPAL FINDINGS CD62P(+) platelets and MPA were...

Journal: :Annals of the Rheumatic Diseases 2023

Background Macrophages strongly contribute to the pathogenesis of rheumatoid arthritis (RA), initiating inflammatory response, join damage, but also may promote resolution inflammation and restoration tissue immune-homeostasis [1,2]. This seems be related an unbalanced immunological response mediated by macrophages through their polarization into “classically” “alternatively” activated phenotyp...

Journal: :Journal of Investigative Dermatology 2023

Formation and deposition of immune complexes (ICs) are hallmarks various autoimmune diseases. Detection ICs by IC receptors on leukocytes induces downstream signaling shapes the local response. In many cases pathological relevance is not well understood. We here show that induce a distinct migratory response, i.e., haptokinesis in 6-sulfo LacNAc+ monocytes (slanMo) non-classical (ncMo) but inte...

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