BACKGROUND AND PURPOSE Clinical-diffusion mismatch (CDM; National Institutes of Health Stroke Scale score≥8 and diffusion-weighted imaging lesion volume<25 mL) has been suggested as a surrogate of ischemic brain at risk of infarction and might be used to recognize salvageable ischemic tissue. Our aim was to identify early biomarkers associated with the presence of CDM. METHODS We prospectivel...

INTRODUCTION In the context of an increasing number of multi-centric studies providing data from different sites and sources the necessity for central data management (CDM) becomes undeniable. This is exacerbated by a multiplicity of featured data types, formats and interfaces. In relation to methodological medical research the definition of central data management needs to be broadened beyond ...

Dark matter direct and indirect detection signals depend crucially on the dark matter distribution. While the formation of large scale structure is independent of the nature of the cold dark matter (CDM), the fate of inhomogeneities on sub-galactic scales, and hence the present day CDM distribution on these scales, depends on the micro-physics of the CDM particles. We study the density contrast...

OBJECTIVE To evaluate the usefulness of a mismatch between the severity of acute clinical manifestations and the diffusion-weighted imaging (DWI) lesion in predicting early stroke outcome and infarct volume. METHODS One hundred sixty-six patients with a hemispheric ischemic stroke of <12 hours' duration were studied. The NIH Stroke Scale (NIHSS) score and the volume of DWI lesion were measure...

BACKGROUND AND PURPOSE Perfusion-diffusion (PWI-DWI) mismatch may represent the ischemic penumbra. The complexities associated with perfusion-weighted imaging (PWI) have restricted its use. Mismatch between stroke severity, assessed with the National Institutes of Health Stroke Scale (NIHSS), and the volume of the diffusion-weighted imaging (DWI) lesion (clinical-diffusion mismatch; CDM) has be...

P134 Table Pre-CDM Post-CDM Z score p Value* 3 Months 0.60 (0–6) 0.22 (0–4) 25.58 ,0.001 6 Months 0.86 (0–10) 0.44 (0–5) 25.23 ,0.001 12 Months 1.14 (0–13) 0.79 (0–9) 22.82 ,0.005 *Wilcoxon rank. CDM, chronic disease management. Poster presentations Thorax 2008;63(Suppl VII):A74–A160 A127 group.bmj.com on October 20, 2017 Published by http://thorax.bmj.com/ Downloaded from

OBJECTIVE To investigate the therapeutic effects of repetitive electrical stimulation of the suprahyoid muscles in brain-injured patients with dysphagia. METHOD Twenty-eight brain-injured patients who showed reduced laryngeal elevation and supraglottic penetration or subglottic aspiration during a videofluoroscopic swallowing study (VFSS) were selected. The patients received either convention...