Abstract   Background: The interest in using bacteria as anti- cancer therapeutic agents dates back to the end of the19th century. Some bacteria like Salmonella and Listeria replicate effectively inside malignant cell lines and suppress their growth. The bacterium Streptococcus pyogenes has become medically famous as a flesh-eating pathogen since mid-1980s. It is the causative agent of a life...

Runx3, a member of Runt-related transcription factor (Runx) proteins with tumor suppressor effect, is a tissue–restricted and cancer related transcription factor that regulate cell proliferation and growth, as well as differentiation. In the present study, exogenous Run3 was transiently expressed in AGS (human gastric adenocarcinoma), with undetectable Runx3 protein and in A549 (human lung carc...

introduction: in order to study the morphogenetic role of cell death in the development, a series of comparative studies on the structure of the interdigital membrane of chick (with free digit) and duck (webbed digits) embryos was done. materials and methods: chick embryos ranging from 6.5 to 10 days of incubation (stag 30-36 h-h) and duck embryos ranging from 8.5 to 12 days of incubation at 12...

apoptosis or programmed cell death is a gene regulated phenomenon which is important in both physiological and pathological conditions. it is characterized by distinct morphological features including chromatin condensation, cell and nuclear shrinkage, membrane blebbing and oligonucleosomal dna fragmentation. although, two major apoptotic pathways including 1) the death receptor (extrinsic) and...

in this study the role of cell death in cartilage canal morphogenesis with morphometrical and histological methods was evaluated. the proximal tibial epiphysis of the chick embryos after fixation and decalcification at the 13 th and 18th days of incubation, with thick and semithin sections and h&e; ,tricromason and feulgen staining were studied. the rsulths were showed that cartilage canals wer...