نتایج جستجو برای: cell penetrating peptide

تعداد نتایج: 1805636  

2014
Donghoon Oh Amir Nasrolahi Shirazi Kevin Northup Brian Sullivan Rakesh Kumar Tiwari Marco Bisoffi Keykavous Parang

Many of the reported arginine-rich cell-penetrating peptides (CPPs) for the enhanced delivery of drugs are linear peptides composed of more than seven arginine residues to retain the cell penetration properties. Herein, we synthesized a class of nine polyarginine peptides containing 5 and 6 arginines, namely, R5 and R6. We further explored the effect of acylation with long chain fatty acids (i....

Journal: :Circulation research 2007
Tong Tang H Kirk Hammond

Congestive heart failure (CHF) is the only cardiovascular disease that is increasing in prevalence.1 Patients with CHF who have symptoms with mild activity or at rest (Class III and Class IV) have a poor long-term outcome, with 5-year age-adjusted mortality of 50%.2,3 Heart transplantation has an 80% 5-year survival rate, but only 3000 cardiac transplants are performed in the US each year, wher...

Journal: :Biochimica et Biophysica Acta (BBA) - Biomembranes 2006

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