We present an ideal observer analysis of single word reading in normal readers and central scotoma patients. Using this technique we are able to predict the spatio-temporal pattern of saccades in terms of pixels. This enables us to contrast theories that are impossible to compare using the traditional letter-slot approaches to modelling reading.

Case report A 75-year-old man complained of a sudden and painless decrease of vision in his left eye. He had undergone surgery for an unruptured intracranial aneurysm 20 years earlier and was taking 7 mg/day of systemic prednisolone for rheumatoid arthritis. He had also had diabetic mellitus without retinopathy for 5 years. He was being followed for a left hemianopsia and normal tension glaucom...

Purpose. To investigate the effect of eccentric refractive correction and full aberration correction on both highand low-contrast grating resolution at the preferred retinal locus (PRL) of a single low-vision subject with a long-standing central scotoma. Methods. The subject was a 68-year-old women with bilateral absolute central scotoma due to Stargardt disease. She developed a single PRL loca...

PURPOSE To present a unilateral central visual field defect in a patient with psoriatic arthritis treated with Methotrexate and folic acid supplement, probably induced by toxic posterior optic neuropathy. The scotoma incompletely resolved after cessation of Methotrexate (MTX) therapy. METHODS Serial fundoscopic, perimetric and electrophysiological examination as well as comprehensive neurolog...

Purpose: We compared visual field progression among patients with primary open-angle glaucoma (POAG), normal tension (NTG), and angle-closure (PACG).Methods: A total of 115 POAG, 123 NTG, 92 PACG eyes were retrospectively analyzed. Global VF was evaluated by calculating the changes mean deviations. To examine local deterioration, scotoma enlargement deepening analyzed in superior, inferior arcu...

BACKGROUND Whether prism, especially base-up prism, affects the area of the retina used for fixation in a patient with central scotoma has been a controversial subject for 35 years. Our pilot study employed microperimetry to evaluate the effect of base-up prism on the fixation locus, or preferred retinal locus (PRL), in subjects with central scotoma. METHODS We used a microperimeter to assess...

PURPOSE To investigate the effect of eccentric refractive correction and full aberration correction on both high- and low-contrast grating resolution at the preferred retinal locus (PRL) of a single low-vision subject with a long-standing central scotoma. METHODS The subject was a 68-year-old women with bilateral absolute central scotoma due to Stargardt disease. She developed a single PRL lo...