The role of calcium (Ca2+) and its dependent protease calpain in Aeromonas hydrophila-induced head kidney macrophage (HKM) apoptosis has been reported. Here, we report the pro-apoptotic involvement of calmodulin (CaM) and calmodulin kinase II gamma (CaMKIIg) in the process. We observed significant increase in CaM levels in A. hydrophila-infected HKM and the inhibitory role of BAPTA/AM, EGTA, ni...

Aeromonas hydrophila leads to both intestinal and extraintestinal infections in animals and humans, and the underlying mechanisms leading to mortality are largely unknown. By using a septicemic mouse model of infection, we showed that animals challenged with A. hydrophila die because of kidney and liver damage, hypoglycemia, and thrombocytopenia. Pretreatment of animals with quorum-sensing-asso...

Aeromonas hydrophila is the main reason of epidemic septicaemia for freshwater fish. In the present study, the effect of Aeromonas hydrophila infection on the non-specific immunity of blunt snout bream (Megalobrama amblycephala) was studied. After Aeromonas hydrophila challenge, lysozyme activity was significantly increased at 4 h, 1 d, 3 d, 5 d, 14 d and 21 d. An increased level of lysozyme ac...

The objective of this study was to investigate the effect of chronic exposure to sublethal concentrations of hexavalent chromium (K2Cr2O7) on the immune response and disease resistance of Oreochromis mossambicus (Peters) to bacterial Aeromonas hydrophila infection. Fish (45 to 50 g) were exposed to 0.005, 0.05, 0.5, and 5 mg l(-1) [0.01, 0.1, 1, and 10% LC50, respectively] of hexavalent chromiu...

Outbreaks in fish of motile Aeromonad septicemia (MAS) caused by Aeromonas hydrophila have caused a great concern worldwide. Here, for the first time, we provide two complete genomes of epidemic A. hydrophila strains isolated in China. To gain an insight into the pathogenicity of epidemic A. hydrophila, we performed comparative genomic analyses of five epidemic strains belonging to sequence typ...

Introduction. Aeromonas hydrophila is a gram negative bacillus that is native to aquatic environments that is increasingly reported in humans. This case is remarkable for A. hydrophila with an initial presentation of acute pancreatitis. Case Presentation. A 61-year-old male presented to the emergency department with nausea, vomiting, and abdominal pain for two days. His past medical history was...

Aeromonas hydrophila is one of the most common bacteria associated with the aquatic environment. There are, however, limited data on A. hydrophila infection in crocodilians. The aim of this report is to describe a case of skin lesions and septicaemia associated with A. hydrophila in a Nile crocodile (Crocodylus niloticus). A captive male crocodile in the Zoological Park of Antalya (Turkey) was ...

9. Ketover BP, Young LS, Armstrong D: Septicemia due to Aeromonas hydrophila: clinical and immunologic aspects. Journal of Infectious Diseases 1973, 127: 284-290. 10. Scott EG, Russell CM, Noell Kl', Sproul AE: Aeromonas hydrophita sepsis in a previously healthy man. Journal of the American Medical Association 1978, 239: 1742. 11. BIoch T, Hockstetler M, Waller BF, Clark SA: Aeromonas hydrophil...

Crude ethanol extracts of Acalypha indica, Acorus calamus, Coleus aromaticus, Heliotropium indicum, and Indigofera aspalathoides were screened for antibacterial activity in vitro against the growth of the fish pathogenic bacteria, Aeromonas hydrophila. Terramycin, widely used to control A. hydrophila in aquaculture, was used as a positive control. The herbs A. calamus and I. aspalathoides warde...

Necrotizing Fasciitis (NF) and sepsis shock is a rare disease in human caused by bacteria infection which is detrimental to patients. We report the diagnosis, progress, treatment and prognosis of patients with NF and sepsis shock caused by Aeromonas hydrophila (A. hydrophila). A 64 y old man was admitted for Gustilo type-iii B open fracture of the left tibia and fibula. Debridement and exopexy ...