BACKGROUND Acute schistosomiasis is a systemic hypersensitivity reaction against the migrating schistosomula and eggs. In this report, we describe an atypical outbreak of the disease with severe cases. Transmission occurred in a nonendemic area of Brazil, which became a new focus of transmission due to the in-migration of infected workers. METHODS From December 2009 to March 2010, the 50 pati...

The neglected blood flukes Orientobilharzia spp. belonging to the Platyhelminthes, infect animals in a number of countries of the world, and cause cercarial dermatitis in humans, as well as significant diseases and even death in economically-important animals. MicroRNAs (miRNAs) are now considered to be a key mechanism of gene regulation. Herein, we investigated the global miRNA expression prof...

pathologically important Platyhelminthes include the digenetic trematodes Opisthorchis, Clonorchis, Paragonimus, Fasci%psis and Fascio/a and the cestodes (tapeworms). Ali the schistosomes that mature in man belong to the genus Schistosoma of the family Schistosomatidae, which contains Il other genera, some of which cause cercarial dermatitis (Rollinson & Southgate, 1987). The genus Schistosoma ...

Recently we developed the genus-specific markers of the avian schistosomes of the genus Trichobilharzia, the causative agents of human cercarial dermatitis. The 7 novel genome sequences of T. franki, T. regenti, and T. szidati revealed similarity with genome repeat region of African schistosome Schistosoma mansoni. In the present work we analyzed the 37 new T. szidati sequences to study intrage...

Schistosoma spindale (Montgomery, 1906) has never been reported in Thailand, since this worm was discovered by Montgomery (1906) in two plain cattle (Bos indices) at Muktesar in India. Liston and Soparkar (1918) completed its life cycle in the goat infected with one kind of furcocercous cercariae obtained from a fresh water snail, Planorbis exustus (synonym of Indoplanorbis exustus). In 1960 an...

BACKGROUND During invasion of human skin by schistosome blood fluke larvae (cercariae), a multicellular organism breaches the epidermis, basement membrane, and dermal barriers of skin. To better understand the pathobiology of this initial event in schistosome infection, a proteome analysis of human skin was carried out following invasion by cercariae of Schistosoma mansoni. METHODOLOGY AND RE...

objective: there is some evidence that chronic skin diseases like dermatitis could affect the quality of life of sufferers. in addition, patients with dermatological disorders are at greater risk to develop psychiatric morbidity. the aim of this study was to explore the quality of life in patients with chronic eczematous dermatitis. we also examined the effect of a convenient dermatologic inter...

BACKGROUND Blood flukes (Schistosoma spp.) are parasites that can survive for years or decades in the vasculature of permissive mammalian hosts, including humans. Proteolytic enzymes (proteases) are crucial for successful parasitism, including aspects of invasion, maturation and reproduction. Most attention has focused on the 'cercarial elastase' serine proteases that facilitate skin invasion b...

BACKGROUND The aim of the present study was to survey birds' schistosomes in migratory birds (Anatidae: Anas platyrhynchos) which are the source of the disease in Mazandaran Province, Northern Iran. METHODS A number of mallards were bought from the markets of hunted birds. The respiratory tracts (nasal mucosa) and intestinal blood vessels were studied for adult worms. The nasal mucosa was sep...