نتایج جستجو برای: cerebral protection
تعداد نتایج: 358674 فیلتر نتایج به سال:
Background and Objective: Daily physical activity can reduce the risk of Parkinson's disease. Therefore, the purpose of this research was to study the effect of wheel running exercise on CDNF level in cortex in an experimental model of rats exposed to 6-hydroxydopamine. Materials and Methods: In this experimental study, 30 Wistar rats were randomly divided into four groups: healthy contr...
Peroxisome proliferator-activated receptor gamma (PPARγ) is emerging as a major regulator in neurological diseases. However, the role of (PPARγ) and its co-regulators in cerebrovascular endothelial dysfunction after stroke is unclear. Here, we have demonstrated that (PPARγ) activation by pioglitazone significantly inhibited both oxygen-glucose deprivation-induced cerebral vascular endothelial c...
Objective: A case of symptomatic cervical carotid artery stenosis with persistent primitive hypoglossal artery (PPHA) treated by carotid artery stenting (CAS) with appropriate embolic protection is reported. Case Presentation: The patient was a 65-year-old male presenting with left hemiplegia. MRI revealed infarction in the right cerebral hemisphere, and cerebral angiography demonstrated stenos...
BACKGROUND AND PURPOSE The purpose of this study was to test the hypothesis that nitric oxide is required for preconditioning in an intact animal model of focal ischemia using neuronal and endothelial nitric oxide synthase (nNOS and eNOS) knockout mice. METHODS Cerebral blood flow was measured in wild-type, nNOS knockout, and eNOS knockout mice by hydrogen clearance (absolute) and laser Doppl...
Physostigmine, at 0.1, 0.2 and 0.3 mg/kg, was tested for effect on the survival of mice exposed to 5% O2-95% N2. Some treated animals survived for one hour under the hypoxic atmosphere (2 out of 14 at 0.1 mg/kg and 8 out of 28 at 0.2 and 0.3 mg/kg), an event never observed in untreated controls. The physostigmine-treated animals that died before the hour showed a dose-related increase in surviv...
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