In the aftermath of the Paris Agreement, there is a crucial need for scientists in both thermal physiology and climate change research to develop the integrated approaches necessary to evaluate the health, economic, technological, social, and cultural impacts of 1.5°C warming. Our aim was to explore the fidelity of remote temperature measurements for quantitatively identifying the continuous re...

A significant challenge in modern clinical medicine is that despite the existence of genetic therapies, lack of techniques to deliver them to the body remains a major roadblock. Viral vectors, benign vehicles for therapeutic delivery produced by removing the reproductive and virulence capacities of wild-type viruses, address this obstacle [1]. Unfortunately, if there is no naturally-occurring v...

We illustrate how digital technology can help restore greviously damaged, practically inaccessible, medieval manuscripts. Our example was an important version of the Old English Life of St. Basil the Great now clinging to existence in charred, illegible, disordered, and strangely dispersed fragments.

Microsomal epoxide hydrolase (mEH) is involved in the bioactivation and detoxification of polycyclic aromatic hydrocarbons derived from tobacco smoke and charred meat intake. Two coding region mEH variants located in exon 3 (Tyr113His) and exon 4 (His139Arg) have been described and may affect the enzyme's specific activity. We investigated these polymorphisms and tested interactions with smokin...

An inexpensive video densitometer based on an Apple II microcomputer using commercially available components was developed. The device was used to quantitate charred lipid and colored spots on thin-layer chromatography plates. The method is useful for lipid samples weighing 0.1 to 4 micrograms on high-performance plates and 1 to 20 micrograms on ordinary plates. The software automatically corre...

Preventive excavation in the ancient Forum Iulii city (Fréjus, southern France) 2013 revealed a housing block where very well preserved charred wooden floor was discovered. It laid house dating back to first half of 1st century AD and used as room decorated with painted plaster. destroyed by fire around 70 AD. The ligneous species for its construction (Aleppo pine, Scots beech fir) were charact...