Managing cancer patients requires numerous drugs, such as chemotherapeutic agents and drugs for other chronic diseases. Thus, health teams must be aware of potential drug interactions that may be detrimental to health. This study analyzed the types of non-chemotherapeutic drugs used by cancer patients and screened patients undergoing cancer treatment for anxiety and depression. Methods: This cr...

Therapeutic use of biological response modulators in combination with chemotherapeutic drugs may propose a more efficient way for cancer therapy with fewer side effects. However, the related mechanism has not been well understood. Γ-interferon is a modulator of biological responses that inhibits the growth of malignant cells and mediates their differentiation. In this investigation, T cell lymp...

Purpose: Systemic administration of free chemotherapeutic drugs leads to severe toxic effects, and physiological characteristics of solid tumors restrain the drugs from reaching the hypoxic regions. E. coli Nissle 1917 (EcN) has been known to penetrate the barrier and proliferate in the interface between the viable and necrotic regions of tumors. This study aimed to fabricate a nanoscale minice...

in leukocytes both in vivo and in vitro. Similar studies have been carried out on the in vitro effect of chemotherapeutic drugs; however, relatively few studies have been reported on the in vivo effect of chemotherapeutic drugs on chromosomes.’11 Of the latter group, there were only three cases of bronchogenic carcinoma, all treated with nitrogen mustard.2’9 This study reports chromosome change...

Chemotherapy is the main treatment modality for certain types of cancer. It is important to monitor and ensure that these chemotherapeutic drugs are potent and effective prior to patient administration. The objective of the study is to evaluate the cytotoxic activity and potency of selected commercially available generic anticancer drugs in comparison with originator using various human cancer ...

In this paper, we consider a tumor growth model with the effect of tumor–immune interactions and chemotherapeutic aswell as immunotherapeutic drugs. In ourmodel there are four compartments, namely tumor cells, immune cells, chemotherapeutic drug concentration and immunotherapeutic drug concentration. The dynamical behaviour of our system by analyzing the existence and stability of our system at...

Electrochemotherapy (ECT) is an effective local tumor therapy performed by the administration of chemotherapeutic drugs followed by the application of local high-voltage electric pulses.1, 2 The electric pulses cause transient structural changes (electroporation) of tumor cell membranes and thus increase the entrance of the chemotherapeutic drugs. This potentiates the chemotherapeutic effect an...