This cohort study was conducted to evaluate the accuracy of parental and child's reports of changes in asthma symptoms. Fifty three asthmatic children and their parents were interviewed at enrollment and after 4 and 8 weeks. The outcomes were parental and child's reports of changes in asthma symptoms, changes in mean daily symptom scores and changes in pulmonary function. Among patients 6 to 10...

Thirty eight, chronic, perennial asthmatic children were prospectively examined every six months for a mean 8.9 years to clarify the relation between clinical asthma and puberty. Improvement in the disease occurred independent of puberty but the rate of improvement was appreciably greater during puberty. This led to speculation that improvement in childhood asthma could be associated with an im...

The Merck Childhood Asthma Network, Inc conference titled "State of Childhood Asthma and Future Directions: Strategies for Implementing Best Practices" was held December 13 to 14, 2006. Here we summarize the presentations and recommendations for systems approaches from that conference and discuss current asthma care.

Background Observational evidence suggests that intake of fruits, and of dietary antioxidants would be protective against symptoms and severity of asthma in children. Intervention studies with single or combined antioxidant supplements have so far been disappointing. To date, there have been no interventions using fresh fruit on asthmatic children. We plan to carry out a 3 month randomised cont...

The present birth cohort study investigated whether or not childhood wheeze and asthma are associated with parental exposure to occupational sensitisers that cause asthma. Parental occupation, from the Avon Longitudinal Study of Parents and Children (ALSPAC), was related to wheeze, asthma, ventilatory function, airway responsiveness and atopic sensitisation in children aged 0-102 months. Occupa...

Asthma is the commonest and most important chronic non-infectious disease in childhood and it has become more prevalent in recent years. There is a shortage of studies in relation to early childhood and so, as part of the INAIRCHILD project, this cross-sectional study aimed to assess the prevalence of asthma and its associated risk factors, namely demographic, environmental, psychosocial and cl...

Asthma is a syndrome that includes several disease variants. Definition of asthma is a chronic disorder of the lung with variable airway obstruction, wheeze/cough, and an underlying inflammatory process with remodeling. It appears that atopic genes are not necessarily directly related to childhood asthma. Airway epithelial cells express genes that encode proteins directly related to asthma. Mat...

OBJECTIVE To investigate differences in self-focused attention between college students with childhood-onset asthma and a group of healthy controls and to determine whether self-focused attention mediates the relationship between illness uncertainty and psychological distress among individuals with asthma. METHODS Forty-two adolescent and young adult participants with childhood-onset asthma a...

Bronchopulmonary dysplasia (BPD) and very low birth weight (VLBW) are associated with increased incidences of asthma and pulmonary dysfunction in childhood. However, no studies exist which examine asthma risk factors in children who were VLBW infants and did not have BPD. To address this issue, we assessed the asthma incidence and risk factors for asthma in 117 children (approximate mean age of...