Evidence supporting seizure-related behaviors in dogs is emerging. The methods of seizure response dog (SRD) training programs are unstudied. A standardized survey was retrospectively applied to graduates of a large SRD program. Subjective changes in quality of life (QOL) parameters were explored. Data were captured on animal characteristics, training methods, response and alerting behaviors, e...

Antiepileptic drug (AED) chronotherapy involves the delivery of a greater AED dose at the time of greatest seizure susceptibility usually associated with predictable seizure peaks. Although research has proven AED chronotherapy, commonly known as differential dosing, to be safe, well tolerated, and highly effective in managing cyclic seizure patterns in selected childhood epilepsies, convention...

Background: Seizures in childhood absence epilepsy (CAE) are usually easily controlled with anti-seizure medications (ASMs). Factors predictive of treatment resistance remain unclear. Our objectives were to assess prevalence neuropsychiatric problems and factors influencing refractoriness a cohort CAE at single centre. Methods: We retrospectively reviewed patients (ILAE 2017 classification) dia...

Febrile seizures are the most common seizure disorder in childhood, affecting 2-5% of children. Simple febrile seizure is defined as a short (<15 min) generalized seizure, not recurring within 24 h, that occurs during a febrile illness not resulting from an acute disease of the nervous system in a child aged between 6 months and 5 years, with no neurologic deficits and no previous afebrile seiz...

Sixty-five children with seizure disorders, who had been treated with multiple anticonvulsants but were poorly controlled, were selected from the Montreal Children's Hospital Convulsive Disorder Clinic and Neurology Service and were treated with sodium valproate (valproate). All types of seizure disorders were included in the group. Rapid oral absorption of the drug lead to peak plasma levels i...

Mechanisms underlying seizure cessation remain elusive. The Lennox-Gastaut syndrome, a severe childhood epileptic disorder, is characterized by episodes of seizure with alternating epochs of spike-wave and fast run discharges. In a detailed computational model that incorporates extracellular potassium dynamics, we studied the dynamics of these state transitions between slow and fast oscillation...

Vol. 1, No. 4 ■ May 2001 U ntil quite recently, the seizure disorders of childhood were broadly associated with generalized disruptions in brain maturation and, by association, the complete range of behavioral and intellectual deficits common in children with epilepsy. This concept of pediatric epilepsy as a cause of diffuse cognitive problems was supported by several lines of evidence as well ...

febrile convulsion (fc) is the most common seizure disorder in childhood. white blood cell (wbc) and erythrocyte sedimentation rate (esr) are commonly measured in fc. trauma, vomiting and bleeding can also lead to wbc and esr so the blood tests must carefully be interpreted by the clinician. in this cross sectional study 410 children(163 with fc), aged 6 months to 5 years, admitted to bahrami c...

BackgroundRecent advances in respiratory management have improved survival for patients with Fukuyama congenital muscular dystrophy (FCMD), characterized by and brain malformation. Previous studies reported that more than half of exhibit seizures childhood. However, little is known about epilepsy after childhood.MethodsTo elucidate the long-term clinical course epilepsy, we retrospectively revi...