A new learning algorithm for feedforward networks, learning by choice of intern al represent at ions (C HIR), was recently introduced [1,2]. W hereas many algor it hm s red uce th e learning proce ss to minimizing a cost function over t he weights, our method treats th e internal representations as the funda ment al ent it ies to be determi ned. T he algo rithm applied a sea rch procedure in th...

The avian IgY antibody isotype shares a common ancestor with both mammalian IgG and IgE and so provides a means to study the evolution of their structural and functional specialisations. Although both IgG and IgE bind to their leukocyte Fc receptors with 1:1 stoichiometry, IgY binds to CHIR-AB1, a receptor expressed in avian monocytes, with 2:1 stoichiometry. The mutagenesis data reported here ...

The chiral WZNW symplectic form Ω ρ chir is inverted in the general case. Thereby a precise relationship between the arbitrary monodromy dependent 2-form appearing in Ω ρ chir and the exchange r-matrix that governs the Poisson brackets of the group valued chiral fields is established. The exchange r-matrices are shown to satisfy a new dynamical generalization of the classical modified Yang-Baxt...

Screening a diverse, combinatorial library of ca. 5000 synthetic dimer and trimer N-(substituted)glycine "peptides" yielded novel, high-affinity ligands for 7-transmembrane G-protein-coupled receptors. The peptoid library was efficiently assembled using readily available chemical building blocks. The choice of side chains was biased to resemble known ligands to 7-transmembrane G-protein-coupled...

Learning by choice of internal representations (CHIR) is a learning algorithm for a multilayer neural network system, suggested by Grossman et al, [1,2) and based upon determining the internal representations of the system as well as its internal weights. In this paper, we propose an energy minimization approach whereby the internal representations (IR) as well as the weight matrix are allowed ...

haematologica/journal of hematology vol. 88(05):may 2003 597 associated with intracellular redox changes and elevated plasma tumor necrosis factor-α concentration. Br J Haematol 1997;99:625-31. 8. G, Finazzi S, Maiolo AT. Folate measurement in patients on regular hemodialysis treatment. Am J Kidney Dis 1999; 33:492-7. 9. Trotti R, Carratelli M, Barbieri M, Micieli G, Bosone D, Rondanelli M, et ...