The detection and discrimination of chiral analytes has always been a topical theme in food pharmaceutical industries environmental monitoring, especially when dealing with drugs pesticides, whose enantiomeric nature assessment is crucial importance. typical approach matches novel receptors designed ad hoc for the target enantiomer emerging nanotechnologies. massive synthetic efforts requested ...

Porphyrinoids are extremely attractive for their electronic, optical, and coordination properties as well versatile substitution at meso/β-positions. All these features allow porphyrinoids to behave chiroptical hosts chiral recognition by means of non-covalent interactions towards guests. Over the years, discrimination molecules such amino acids, alcohols, amines, hydroxy-carboxylic etc. has ar...

Understanding the interaction of pharmaceutical agents to DNA is essential for underlying their mode of action, site, sequence and structural specificity of their binding reactions. Chirality of a complex is a pre–requisite criterion for an appropriate model drug design, since usually two enantiomers of the same metal complex have different binding constants and recognition properties. Interact...