1. Dakin's hypochlorite and chloramine-T solutions will protect pigeons against multiple fatal doses of the toxin of Bacillus welch when the antiseptic and the toxin are mixed in vitro and allowed to stand in contact for 5 minutes before injection. 2. The detoxicating action of the solutions is demonstrable also in the presence of serum. 3. Phenol solution, 0.25 per cent, has no such action.

Nitrile oxides were generated by the catalytic dehydrogenation of aromatic aldehyde oximes 2a-g with chloramine-T as oxidizing agent. The 1,3-dipolar cycloaddition of in situ generated nitrile oxides with ethyl oleate 1 produced a series of new ethyl 8-(3-aryl-4-octyl-4,5-dihydroisoxazol-5-yl)octanoate 3a-g in 6584% yield. Some of the synthesized cycloadducts have exhibited moderate to good ant...

2,10-Disubstituted phenothiazines are the best drugs in psychiatry. Several methods for their analysis have been reported in the literature. The official methods are based on non-aqueous titration or spectrophotometry. Various oxidizing agents have been used for the spectrophotometric determination of 2,10-disubstituted phenothiazines, e.g. Ce(SO4)2, NH4VO3, K2S208, KIO4, KIO3, KBrO3, FeCl3, Na...

The goal of the study aims to evaluate newly radioiodinated candesartan (CAN) as a potential cardiovascular tracer. CAN was labeled using 125 I with chloramine-T (Ch-T) and N-bromosuccinimide (NBS) with full characterization of cold Iodo-candesartan. Factors such as pH, reaction temperature, reaction time, substrate, and oxidizing agent amounts were studied to optimize the radioiodination of CA...

Disinfection by-products (DBPs) are potentially toxic compounds formed when drinking water is treated with disinfectants, such as chlorine or chloramine. A large proportion of the exposure to DBPs ...

The aim of our research was to develop a chromatographic method for simultaneous determination of five substances used as disinfectant agents. Biphenyl-2-ol (BPh), chloramine T (ChT), 4-chloro-3-methylphenol (4C3MPh), triclosan (TCS), and triclocarban (TCC) were determined using high-performance liquid chromatography. Chromatographic analyses were carried out on a Develosil RP Aqueous AR-5 RP-3...