BACKGROUND AND OBJECTIVES Food contamination by aflatoxins is an important food safety concern for agricultural products. In order to identify and develop novel antifungal agents, several plant extracts and isolated compounds have been evaluated for their bioactivities. Anti-infectious activity of Piper betle used in traditional medicine of Malaysia has been reported previously. MATERIALS AND...

Piroxicam (PX), an anti-inflammatory drug, exhibits poor water solubility, dissolution and flow properties. Thus, the aim of the present study was to improve the solubility and dissolution rate of PX by freeze drying technique using dimethylformamide (DMF), chloroform and water as co-solvent system. The prepared crystals containing PX were evaluated for DMF and chloroform solvent residual by ga...

BACKGROUND Ultrasonic irrigation has been proved for its remarkable cleaning efficiency in the field of endodontics. But its role in endodontic re-treatment has been understated. There is not much data available to understand the effect of ultrasonic irrigation for the evaluation of cleanliness of dentinal tubules when it is used with or without chloroform, a gutta percha solvent during endodon...

Graphene oxide (GO) sheet is used as a novel substrate for dip-pen nanolithography (DPN). After GO is transferred onto SiO(2) using the Langmuir-Blodgett technique, CoCl(2) is patterned on both GO and exposed SiO(2) substrates simultaneously by DPN, which is used for growth of different structured carbon nanotubes.

Dipyridamole (DIP) is a well-known pharmaceutical drug used as a coronary vasodilator and anti-platelet agent in clinics for treating several cardiovascular diseases. Primarily, the therapeutic effects of the drug are attributed to its antioxidant potency. In this research, we aim to declare the unknown antioxidant mechanism of DIP as well as its potent chain-breaking antioxidant activity in po...

Miniaturized combined arrays of three different pH indicators allowing for sensitive, robust and broad-range acidity detection are prepared by parallel dip-pen nanolithography, which proves the potential of this technique to fabricate multiplexed platforms at the micro- and nanoscale that can act as sensors.

PURPOSE Among the hearing loss patients, we can confirm that the hearing loss of the specific frequency decreases, such as the 2000Hz notch in otosclerosis and the 4000Hz notch (c5-dip) in noise-induced hearing loss. The 1000Hz notch (c3-dip), however, is rarely studied. We fortuitously encountered a group of patients with a 1kHz hearing loss and report it with a review of the literature. MET...

In the past decades, many methods have been developed to synthesize zero- dimensional  nanoparticles, quasi–one–dimensional (1D) CuO nanostructures, such as metal organic deposition technique,  microwave irradiation, sol-gel-like dip  technique, reverse micelle-assisted route, chemical method, and simple template free solution route. Among those synthesis methods, hydrothermal and chemical reac...