نتایج جستجو برای: chondroitinase abc

تعداد نتایج: 15466  

Journal: :Tissue engineering. Part A 2009
Roman M Natoli Christopher M Revell Kyriacos A Athanasiou

Collagen content and tensile properties of engineered articular cartilage have remained inferior to glycosaminoglycan (GAG) content and compressive properties. Based on a cartilage explant study showing greater tensile properties after chondroitinase ABC (C-ABC) treatment, C-ABC as a strategy for cartilage tissue engineering was investigated. A scaffold-less approach was employed, wherein chond...

2012
Filippo Rossi Pietro Veglianese Marco Santoro Simonetta Papa Cristina Rogora Valentina Dell’Oro Gianluigi Forloni Maurizio Masi Giuseppe Perale

In the injured spinal cord, chondroitin sulfate proteoglycans (CSPGs) are the principal responsible of axon growth inhibition and they contribute to regenerative failure, promoting glial scar formation. Chondroitinase ABC (chABC) is known for being able to digest proteoglycans, thus degrading glial scar and favoring axonal regrowth. However, its classic administration is invasive, infection-pro...

2014
Arash Sarveazad Mehrdad Bakhtiari Asrin Babahajian Atusa Janzade Ali Fallah Fateme Moradi Mansoureh Soleimani Mohammadreza Younesi Farjam Goudarzi Mohammad Taghi Joghataei

OBJECTIVES Spinal cord injury (SCI) is one of the most serious clinical diseases and its treatment has been a subject of interest to researchers. There are two important therapeutic strategies in the treatment of SCI: replacing lost tissue cells through cells implantation and scar elimination. Therefore, in this study we used human adipose-derived stem cells (hADSCs) implantation and injection ...

Journal: :The Tohoku journal of experimental medicine 1974
T Orii Chiba R Minami K Sukegawa T Nakao

ORII, T., CHmA, T., MINAMI, R., SUKEUAWA, K. and NAKAO, T. Hyper glycopeptiduria in Genetic Mucolipidoses. Tohoku J. exp. Med., 1974, 112 (4), 373-380 -Urinary cetylpyridinium chloride (CPC)-precipitates and non-CPCprecipitates in normal male children and seven patients with a new type of mucolipidosis, GM1-gangliosidosis type 1, I-cell disease, Hurler syndrome, Morquio syndrome, Gaucher's dise...

Journal: :Archives of histology and cytology 1997
T Yoshikawa K Nishida T Doi H Inoue A Ohtsuka T Taguchi T Murakami

Negative charged sites in the normal rabbit articular cartilage were investigated using cationic colloidal iron methods. In light microscopy of the cartilage stained with the colloidal iron at pH 1.5, a distinct Prussian blue reaction was observed in the pericellular matrix, and a weak blue reaction in the territorial and interterritorial matrices. At pH 7.0, a diffuse Prussian blue reaction wa...

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