Evolution of an osteoma may result in neurosensory detachment, deossification, and choroidal neovascularization (CNV). The authors report a rare case of choroidal osteoma with CNV associated with a deep non-conforming focal choroidal excavation. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:944-947.].

PURPOSE To compare the preferential hyperacuity perimeter (Preview PHP; Carl Zeiss Meditec, Dublin, CA) with the original Amsler grid in the detection of choroidal neovascularization (CNV) in patients with age-related macular degeneration (AMD). METHODS Patients were classified into groups, based on the severity of the age-related macular degeneration and underwent preferential hyperacuity pe...

OBJECTIVES To assess the impact of thrombospondin 1(TSP1) deficiency on choroidal neovascularization (CNV)and to determine whether administration of a TSP1 antiangiogenic mimetic peptide attenuates CNV. METHODS The impact of TSP1 deficiency on laser induced CNV was assessed using wild-type (TSP1 +/+) and TSP1-deficient (TSP1 −/−) mice. Three laser burns were placed in each eye of TSP1 +/+ and...

OBJECTIVE To determine the prevalence and visual significance of cystoid macular edema (CME) in eyes with subfoveal neovascular age-related macular degeneration using optical coherence tomography (OCT). MATERIALS AND METHODS The medical records of 61 consecutive patients initially seen with nondisciform subfoveal neovascular age-related macular degeneration were retrospectively reviewed. All ...

OBJECTIVE To report the functional and anatomical outcome of 20 patients who underwent surgical removal of choroidal neovascularization combined with transplantation of autologous iris pigment epithelial cells to the subretinal space 3 years after treatment. METHODS Freshly isolated autologous iris pigment epithelial cells were translocated to the subretinal space in 20 patients after membran...

Choroidal osteoma is a unique tumor that comprises mature bone in the circumpapillary or macular region.1 Choroidal osteoma showed evolution with change in clinical features over many years, and cases of tumor growth, tumor decalcification or involution, and related choroidal neovascularization (CNV) were documented.1-4 Herein, we present a case of choroidal osteoma with serous retinal detachme...

A 16 year old female presented to the New England Eye Center with a chief complaint of decreased vision and metamorphopsia in the left eye. The symptoms started three months prior to presentation and remained unchanged from onset. There were no other visual complaints at the time of presentation. She denied any prior ocular history; this was her first eye exam. On review of systems, there was n...