Background: Rheumatoid arthritis is the most prevalent chronic rheumatologic disease of children. The quality of life (QOL) in these individuals is affected by physical pain, discomfort, treatment complications, and frequent absences from school leading to academic failure. No research similar to the present investigation was performed in this area. Aim: ...

Arthritis in childhood is not uncommon. Estimates of the annual incidence of arthritis vary widely, but for all forms of chronic arthritis it is probably between 5 and 10 per 100 000 children aged 16 years or younger. 2 Acute forms of arthritis are perhaps four times more common. Most paediatricians will therefore see several patients with arthritis each year. The aim of this paper and part 2 o...

Microbial agents induce arthritis through mechanisms such as direct infiltration of tissue and by inducing autoimmune phenomena. The mechanisms involved in this last type of arthritis have been investigated. In experimental models of adjuvant and reactive arthritis, the involvement of T cells in some cases mycobacteria in the development of arthritis have been confirmed. Cross-reactivity betwee...

Differentiating between arthralgia and arthritis is of the utmost importance for the pediatrician. Proper joint exam, aided by adequate use of laboratory and imaging tests, makes this differentiation possible. Renee F. Modica, MD, Sukesh Sukumaran, MD, and myself give a comprehensive review of the joint exam in children, providing illustrations of the exam maneuvers and interpretations of diffe...

OBJECTIVE Evidence suggests that substance P (SP) is involved in chronic joint inflammation, such as the pathogenesis of rheumatoid arthritis and osteoarthritis. The goal of the research was to evaluate the correlation between chronic pain and changes in the SP level in patients with chronic inflammation of the connective tissue. METHODS Patients with osteoarthritis and rheumatoid arthritis w...

Doctor Vasudevan is Clinical Professor of Physical Medicine & Rehabilitation, Medical College of Wisconsin, and Clinical Professor of Orthopedics and Rehabilitation, University of Wisconsin-Madison. He was a member of American Pain Society panel on developing guidelines for the management of pain in Osteoarthritis, Rheumatoid Arthritis, and Juvenile Chronic Arthritis. Doctor Potts is a resident...

Rheumatoid arthritis is a chronic inflammatory autoimmune disease that affects approximately 0.5-1% of the general population and leads to chronic synovial inflammation, destruction of cartilage and bone, and disability. The heritability of rheumatoid arthritis has been estimated to be about 60%, while the contribution of HLA to heritability has been estimated to be 11-37%. Other genes, such as...

Two 19 year old patients with juvenile chronic arthritis developed liver toxicity during treatment with sulphasalazine. A significant increase in the levels of liver enzymes in serum samples was noticed in relation to the initiation of treatment in one patient and to the increase in dose in the second. The enzymes returned to normal levels 14 days after the drug had been stopped. A rechallenge ...

A case is reported of primary late-onset hypogammaglobulinaemia associated with a chronic seronegative, nonerosive arthritis, which was complicated by an episode of septic arthritis due to Mycoplasma pneumoniae. The patient had subcutaneous nodules which have not been regarded previously as a feature of the chronic arthritis associated with hypogammaglobulinaemia. The diagnosis of septic arthri...

please cite this article as: shafeian sh, bandehpour m, mirzaahmadi s, tofighi a. identification of anaerobic bacteria in patients with rheumatoid arthritis. . novel biomed 2013;1(2):39-42. background : there is a report about the 2-5% prevalence for septic arthritis by anaerobic bacteria. the relevance between synivitis and intestinal microbial flora has been a hypothesis for ten years. the pc...