conclusions according to the results obtained in our study, advanced age, higher bmi, ast, alt, and hbv-dna levels, and low albumin and platelet levels are correlated with advanced fibrosis in patients with chb. objectives this study evaluated the correlation between hepatic fibrosis and routine laboratory values in patients with chronic hepatitis b. patients and methods the files of 456 patien...

background: hepatitis e virus is an enterically transmitted virus that is endemic in south asia and this virus is one of the most important cause of acute hepatitis in this region. although hepatitis e virus (hev) is not a leading cause for chronic hepatitis, the role of hev in exacerbation of chronic liver disease is certain. materials and methods: 100 cirrhotic cases (50 hepatitis b and 50 he...

aim : to investigate if hepatic iron content influences the response to therapy in patients with chronic hepatitis c or b. background : it seems that the presence of elevated body iron stores and, in particular, elevated hepatic iron levels, is one of the strongest predictors of resistance to interferon treatment for chronic hepatitis c or b. patients and methods : two hundred and one patients ...

Background and Aims: Hepatocellular carcinoma (HCC) is one of the most important common cancers in the world. The main etiology of this cancer in developing and third world countries is due to the infection with hepatitis B and C viruses. Hepatitis B and C viruses (HCV) would both cause liver cancer but the incidence of the disease in relation to the age and gender has not been determined. The ...

abstract   background: hepatitis b virus infection is an important cause of liver morbidity and mortality worldwide. hdv changes the natural course of hbv. the prevalence of hdv infection wasn’t determined in the various groups of hbv infection (carriers, acute hepatitis, chronic hepatitis, cirrhosis and hcc) in iran. we aimed to research the prevalence of hepatitis d virus infection in various...

background although certain hbv mutations are known to affect the expression of hepatitis e antigen, their association with hbv viral level or clinical outcomes is less clear. objectives we evaluated associations between different mutations in the basal core promoter (bcp) and pre-core (pc) regions of hbv genome and subsequent changes in hbv viral dna level over seven years in a population of u...

introduction various types of dermatological manifestations have been reported due to hepatitis c virus (hcv) infection and anti­hcv therapy. some of them have been described during ifn-based therapies. peg-ifn-α-2a/rbv combination is used as the international standard of treatment for hcv infection for a long time. the combination therapy yields an adverse-event profile similar to standard int...

conclusions this study indicates that 2.9% of hemodialysis patients had obi, which is considered as a major public health problem worldwide. moreover, we observed three mutations in s region, including t127p, p153l, and f170s, which caused obi. this study is first to report a mutation analysis of hbv in hemodialysis patients in southwestern iran. these results indicate that current screening te...

background: hepatic steatosis is commonly observed in patients with chronic hepatitis c (chc). many studies indicate a relationship between steatosis and fibrosis progression. the aim of this study was to analyze the prevalence of hepatic steatosis and related factors in iranian chc patients.   methods: one hundred and fifteen consecutive patients with chc were enrolled which were treatment-naï...