Tuberculous meningitis (TBM) and cryptococcal meningitis (CM) are two of the most common types of chronic meningitis. This study aimed to assess whether chronic neuro-psychological sequelae are associated with micro-structure white matter (WM) damage in HIV-negative chronic meningitis. Nineteen HIV-negative TBM patients, 13 HIV-negative CM patients, and 32 sex- and age-matched healthy volunteer...

Cortical lesions constitute an important part of multiple sclerosis pathology. Although inflammation appears to play a role in their formation, the mechanisms leading to demyelination and neurodegeneration are poorly understood. We aimed to identify some of these mechanisms by combining gene expression studies with neuropathological analysis. In our study, we showed that the combination of infl...

case as we see it in the child of school age and also mentions the high inciden0^, convulsions in infancy and the difficulty of diagnosis in the more chronic type of ^^ ingococcal meningitis. Reference to modern standard text-books shows a uniformity in the clinical description, " The onset of the disease is generally su ^ and is characterized by vomiting, headache, sometimes pain in the back, ...

Aseptic meningitis is a recognised complication after posterior fossa surgery. It is often self limiting but occasionally runs a protracted course requiring repeated CSF examination to exclude infection, and treatment with systemic steroids. A patient is described with aseptic meningitis after posterior fossa surgery who underwent posterior fossa re-exploration nearly 3 years after the initial ...

A 60-year-old man with chronic myelomonocytic leukemia was admitted for bacterial meningitis. Initial cranial CT and CT angiography (figure, A) were normal. Four days after admission, the patient became comatose. A subsequent cranial CT (figure, B) revealed a subarachnoid hemorrhage, and CT angiography (figure, C) showed a newly developed aneurysm of the basilar artery. We diagnosed a mycotic a...

Congenital, infectious, toxic, and demyelinating disorders are common etiological causes of deafness. Tuberculous meningitis, as one of the infectious causes, should be considered in the differential diagnosis since tuberculosis represents an endemic public health problem in developing countries. Multiple cranial nerve palsies can be expected due to basal meningitis; however, presentation with ...

Gram-negative bacillary meningitis (GNBM) is commonly seen in infants and neonates. However, GNBM can cause severe meningitis in adults, although rarely. It usually occurs after central nervous system trauma and neurosurgical procedures. The immunocompromised, the elderly, or patients with chronic diseases are at high risk.1,3 Numerous antibiotics have been tried in the treatment of GNBM, but o...

background: acute bacterial meningitis is among serious infections of the central nervous system (cns). the early diagnosis and empiric antibiotic treatments have led to a reduction in morbidity and mortality rates. pcr and the enzymatic digestion of 16s rdna fragment following the pcr by universal primers led up fast and sensitive determination. the aims of the present study was to improve our...