Beta 2 agonists reduce airway hypersensitivity to bronchoconstrictor stimuli acutely in patients with asthma and chronic obstructive lung disease. To determine whether these drugs also protect against excessive airway narrowing, the effect of inhaled salbutamol on the position and shape of the dose-response curves for histamine or methacholine was investigated in 12 patients with asthma and 11 ...

Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD), asthma, cystic fibrosis (CF) and interstitial lung diseases (ILD), affect many individuals worldwide. Patients with these chronic lung diseases are susceptible to respiratory lung infections and some of these viral infections can contribute to disease pathogenesis. This review highlights the associations of lung infect...

Smoking is a risk factor for disease that contributes the most to lung and respiratory diseases. Lung related with cigarette smoke can be classified as COPD (Chronic Obstructive Pulmonary Disease) several types of interstitial such pulmonary langerhans cell histiocytosis, bronchiolitis, desquamative pneumonitis fibrosing disease. This literature review aims shed light not only causes inflammati...

26 Background: Glucocorticoid function is markedly impaired in the lungs of patients with 27 chronic obstructive pulmonary disease. This reduction in glucocorticoid sensitivity may be 28 due to an oxidant-mediated elevation in phosphoinositol 3-kinase  signaling. 29 Objective: To determine the role of phosphoinositol 3-kinase  in the reduced glucocorticoid 30 responsiveness in chronic obstruc...

Introduction: Chronic obstructive pulmonary disease (COPD) secondary to sulfur mustard gas poisoning, known as mustard lung, is a major late pulmonary complications in chemical warfare patients. Serious comorbidities like dyslipidemia are frequently encountered in COPD. The aim of this study was to measure the serum lipid profile and evaluate the relation of lipid parameters with the severity o...

Pulmonary mucociliary clearance is an essential defense mechanism against bacteria and particulate matter. Mucociliary dysfunction is an important feature of obstructive lung diseases such as chronic obstructive pulmonary disease, asthma, cystic fibrosis, and bronchiectasis. This dysfunction in airway clearance is associated with accelerated loss of lung function in patients with obstructive lu...

overlap syndrome, which is known as the coexistence of chronic obstructive pulmonary disease (copd) and obstructive sleep apnea (osa), was first defined by flenley. although it can refer to concomitant occurrence of any of the pulmonary diseases and osa, overlap syndrome is commonly considered as the coexistence of osa and copd. this disease has unique adverse health consequences distinct from ...

background : there is little evidence about the role of zafirlukast (a highly selective ltd4 antagonist) in chronic obstructive pulmonary disease (copd). the zafirlukast can reduce the need for short-acting rescue β2 agonists, produce fewer exacerbations of asthma and increased quality of life as possible benefits treatment for asthma. the aim of our study was to evaluate the effects of zafirlu...

chronic obstructive pulmonary disease (copd) is a public health problem worldwide. increased energy and protein needs, decreased energy and protein intake are common in copd patients. adequate intake is essential to improve pulmonary function and immune system, prevention of weight loss and maintaining muscle mass and strength. assessment of energy and protein intake and its relationship with p...

normal 0 false false false en-us x-none ar-sa background: we investigated the difference of clinical practice pattern between end‑stage chronic obstructive pulmonary disease (copd) patients with and without palliative care at the end of life in taiwan. materials and methods: a total of 91 copd patients who died in an acute care hospital were enrolled from one community teaching hospital in no...