Abstract Sialolithiasis along with sialadenitis is one of the commonly occurring salivary gland disorders. Sialadenitis an inflammatory disease glands. It usually occurs insidiously causing pain to patient and may lead development fibrous mass gland. The cause most due duct caliculi which termed as sialolith or stones causes statis saliva in ducts. This condition accompanied by tenderness invol...

Sarcoidosis is a systemic granulomatous, non-infectious multifocal disorder of unknown etiology, characterized by the presence of non-caseous epithelioid granuloma in the tissue. About 20 to 40% of the patients are symptom-free and their disease is found through routine radiographic tests. The hypothetical causal agents include environmental and autoantigen aspects. The goal is to report a rare...

We investigated the role of the major histocompatibility complex (MHC) region in the specificity of autoimmunity by analysing specifically the development of sialadenitis, but also insulitis, nephritis and autoantibody production in autoimmune-prone nonobese diabetic (NOD) mice where the MHC H2g7 haplotype had been exchanged for the H2q (NOD.Q) or H2p (NOD.P) haplotype. The exchange of H2 haplo...

Background: Only 17 cases of neonatal submandibular sialadenitis have been described in neonates. These infections are frequently caused by gram-positive cocci. We unexpectedly observed multiple cases of sialadenitis and cervical adenitis in our regional NICU within a few years, as staphylococcal aureus infections have become more prevalent in the hospital and community. Therefore, we postulate...

BACKGROUND AND PURPOSE MR sialography has become an alternative imaging technique for ductal salivary gland diseases. We compared the diagnostic accuracies of MR sialography and digital subtraction sialography in patients with successful completion of both examinations and benign salivary gland disorders. METHODS In a prospective study, we attempted to examine salivary glands in 80 patients w...

BACKGROUND Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) induces apoptosis of tumor cells but not normal cells; its role in normal non-transformed tissues is unknown. OBJECTIVE To evaluate the role of apoptosis mediated by TRAIL and TRAIL-receptor (TRAIL-R) system in lymphocytic sialadenitis in patients with Sjögren's syndrome. METHODS The expression of TRAIL and TRAIL-R1,...

Botulinum toxin (BTX) is a neurotoxic protein produced by Clostridium botulinum, an anaerobic bacterium. BTX therapy is a safe and effective treatment when used for functional silencing of the salivary glands in disorders such as sialoceles and salivary fistulae that may have a post-traumatic or post-operative origin. BTX injections can be considered in sialoceles and salivary fistulae after th...