The aim of this study was to isolate and identify secondary metabolites from Sonchus brachyotus evaluate their antioxidant anti-inflammatory activities. In study, we isolated three flavonoids a 70% EtOH extract by Medium Pressure Liquid Chromatography (MPLC) prep-High-Performance (HPLC). To the biological activities (an-tioxidant anti-inflammatory) these flavonoids, in vitro inhibitory against ...

Background and objectives: Marrubium parviflorum Fisch. & C.A.Mey. (Lamiaceae) is a medicinal plant with documented antioxidant and analgesic effects distributed in Iran and Turkey. In the present study, the aerial parts of this species were subjected to phytochemical analysis, as well as antioxidant activity assays. Methods: Antioxidant activity of th...

To investigate the adipogenesis inhibitory effect on lipid accumulation, 3T3-L1 cells were treated with fractions and isolated flavonoids of Spirodela polyrhiza. An ethanol extract of S. polyrhiza was fractionated into three fractions. The butanol soluble fraction (SPB) exhibited potent antiadipogenesis activity and decreased C/EBPα and PPARγ protein expression level in 3T3-L1 cells without sig...

With N-acetyl-D-glucosamine 8....................................................................... S31 With D-glucose 9................................................................................................ S33 With methyl-β-D-glucoside 10......................................................................... S35 With L-mannose 12.......................................................

Flavonoids is an intensively studied group of natural compounds with antioxidant, antineoplastic, antihyperglycemic, cardioprotective, and neuroprotective properties. The present study intends to investigate the geroprotective action of three selected flavonoids (naringin, luteolin, chrysin) in two model organisms, Caenorhabditis elegans and Drosophila melanogaster. Luteolin and chrysin were sh...

BACKGROUND The processed roots of Polygonum multiflorum Thunb. (Heshouwu; processed HSW) are commonly used in anti-aging medicine. Few reports have combined chemical profiles with bioactivity to evaluate the quality of the processed HSW. This study aims to integrate chemometric fingerprints of antioxidant activities and high-performance liquid chromatography-diode array detection-chemiluminesce...

The effects of ethanol concentration (0%-100%, v/v), solid-to-solvent ratio (1:10-1:60, w/v) and extraction time (30-180 min) on the extraction of polyphenols from agarwood (Aquilaria crassna) were examined. Total phenolic content (TPC), total flavonoid content (TFC) and total flavanol (TF) assays and HPLC-DAD were used for the determination and quantification of polyphenols, flavanol gallates ...

Flavonoids are structurally diverse and the most ubiquitous groups of polyphenols distributed in the various plants, which possess intensive biological activities. In this study, the interaction mechanisms between four flavonoids containing one glucose unit with similar molecular weight isolated from the Tibetan medicinal herb Pyrethrum tatsienense, namely, apigenin-7-O-β-D-glucoside(1), luteol...

The β-glucosidase gene bgl3a from Myceliophthora thermophila, member of the fungal glycosyl hydrolase (GH) family 3, was cloned and expressed in Pichia pastoris. The mature β-glucosidase gene, which results after the excision of one intron and the secreting signal peptide, was placed under the control of the strong alcohol oxidase promoter (AOX1) in the plasmid pPICZαC. The recombinant enzyme (...