The West African Ebola epidemic has set in motion a collective endeavour to conduct accelerated clinical trials, testing unproven but potentially lifesaving interventions in the course of a major public health crisis. This unprecedented effort was supported by the recommendations of an ad hoc ethics panel convened in August 2014 by the WHO. By considering why and on what conditions the exceptio...

1147 REV NEUROL 1999; 29 (12): 1147-1153 Recibido: 16.11.98. Recibido en versión revisada: 22.10.99. Aceptado: 22.10.99. a Médico neurólogo-neurofisiólogo y psiquiatra. Tulane University-School of Medicine. New Orleans, Estados Unidos. Ex-profesor titular de Fisiología y Biofísica. Universidad de Cartagena de Indias. b Médico interno, monitor de Fisiología y Biofísica de la Universidad de Carta...

Clinical trials are needed globally to reduce disease burdens by helping developing safe and effective new therapies and vaccines. These solutions may be for noncommunicable diseases like cancer and diabetes, or, as is especially needed in the poorest regions of the world, infectious disease. Developing countries are underrepresented in research due to lack of commercial viability and trained r...