Polycystic ovarian syndrome (PCOS) is one of the most common endocrine disorders in women with a heterogeneous clinico-pathologic spectrum characterised by varying degrees ovulatory dysfunction and clinical and/ or biochemical features hyperandrogenism. The etiopathogenesis PCOS remains controversial multiple genetic variants environmental factors interacting together to foster development feat...

Cemento-ossifying fibroma (COF) of maxilla is comparatively rare lesion of the maxillofacial region. There is often a misdiagnosis in the category of fibroosseous lesions, owing to an overlap of clinical, histological and radiographic features amongst the separate entities. We present a case of giant maxillary COF causing extensive disfiguration of the face, along with extensive review of the c...

There are many kinds of extra-axial brain tumors and tumor-like lesions, and definitive diagnosis is complicated in some cases. In this pictorial essay, we present rare and challenging extra-axial brain lesions including neuroenteric cyst, primary leptomeningeal melanomatosis, isolated dural neurosarcoidosis, intradiploic epidermoid cyst, ruptured dermoid cyst, intraventricular cavernoma, and c...

Background: Cutaneous appendageal tumours can arise from either the eccrine, apocrine, hair follicles or the sebaceous glands. Majority of the tumours are benign. Final diagnosis requires a good clinical as well as histpathological correlation. The aim of the present study was to assess the clinicopathological characteristic of these tumours. Materials & Methods: The present study was a retro-p...

OBJECTIVES In this study, we aimed at evaluation of electrophysiological and histopathalogical characteristics of statin-induced muscle injury as well as clinical features of patients who develop this condition in terms of frequency and pattern of evolution. MATERIALS AND METHODS Forty patients (age 39-74 years) including 25 subjects with type 2 diabetes mellitus, 9 with cardiovascular diseas...

Non-Hodgkin’s Lymphoma (NHL) ICD-10 (International Classification of Diseases 10th Revision) categories (C82-85; 96), is a diverse group of neoplasms both in their natural history and response to treatment. They rank fifth in cancer incidence in United States, and are increasing at a rate of almost 7% per year (Zucca et al., 2000). There is large geographical variation in the incidence, histopa...

The clinical and pathologic data of the 221 patients with breast carcinoma primarily treated in the Servico de Cirurgia 3 of Hospital S. Joäo from 1960 to 1979 were reviewed. The 5, 10 and 15-year survival rates of the 215 patients with follow-up information were 63.4%, 48.2% and 20.2%, respectively. Patho logic staging of the axilla was found to be the most important prognostic factor. Tumor s...

BACKGROUND C3 glomerulopathy (C3GP) is characterized by deposition of complement C3 with absence/traces of immunoglobulins in the glomeruli and categorized into dense deposit disease (DDD), C3 glomerulonephritis (C3GN), complement factor H related protein 5(CFHR5) nephropathy etc. Collaborative efforts of pathologists, complement biologists and nephrologists worldwide are expanding the histomor...