Coagulase negative staphylococci (CoNS) are important opportunistic pathogens. Staphylococcus epidermidis, a coagulase negative staphylococcus, is the third leading cause of nosocomial infections in the US. Surface proteins like Microbial Surface Components Recognizing Adhesive Matrix Molecules (MSCRAMMs) are major virulence factors of pathogenic gram positive bacteria. Here, we identified a ne...

Objectives: The purpose of this study was to evaluate the conjunctival bacterial flora and its antibiotic susceptibility pattern in eyes of patients undergoing cataract surgery. Methodology: Conjunctival soap was obtained on the day of surgery before the application of topical anesthetic, antibiotic or povidone-iodine. Culture and antibiotic susceptibility tests were performed. The data was ana...

INTRODUCTION Coagulase-negative staphylococci, commonly Staphylococcus epidermidis, cause 5% of native valve endocarditis. We describe a case due to Staphylococcus lugdunensis, a coagulase-negative staphylococcus identified in 1988, as a first report in Southeast Asia. It was previously misidentified as S. aureus because it is sometimes slide coagulase positive, but always tube coagulase negati...

INTRODUCTION In venous ulcers, the presence of Staphylococcus aureus and coagulase-negative staphylococcus resistance phenotypes can aggravate and limit the choices for treatment. METHODS Staphylococcus isolated from 69 patients (98 ulcers) between October of 2009 and October of 2010 were tested. The macrolide, lincosamide, streptogramin B (MLS B) group resistance phenotype detection was perf...

PURPOSE Urinary stasis is a risk factor for recurrent urinary tract infection (UTI). Homozygous mutant Megabladder (Mgb-/-) mice exhibit incomplete bladder emptying as a consequence of congenital detrusor aplasia. We hypothesize that this predisposes Mgb-/- mice to spontaneous and experimental UTI. METHODS Mgb-/-, Mgb+/-, and wild-type female mice underwent serial ultrasound and urine culture...

Aerobic In clusters ● Coagulase (+): Staphylococcus aureus ● Coagulase (-): Staphylococcus lugdunensis and other coagulase-negative staphylococci In pairs/chains

Methicillin-resistant Staphylococcus aureus (MRSA) remains as the most nosocomial pathogen and is now the emerging problem of community-associated infections. In the present study 100 nasal samples from pediatric patients were subjected to bacteriological and molecular tests for the identification drug resistant Staphylococcus organisms and detection of responsible genes. It revealed that out o...

Ventriculoperitoneal (VP) shunt is one of the most frequently performed procedures in the neurosurgical practice [1]. This simple device results in great improvement in neurological functions and survival of patients with hydrocephalous, at the same time is associated with complications especially infections and malfunctioning. Infections are mainly caused by Coagulase Negative Staphylococcus (...

Background: Coagulase negative staphylococci (CoNS), once considered as non-pathogenic commensal of skin and mucus membrane have emerged as important pathogen. Aim: The aim of this study is to determine species of CoNS and antimicrobial susceptibility pattern of species obtained from various clinical specimens. Materials and Methods: A total of 79 Coagulase negative staphylococci (CoNS) isolate...

A total of 104 coagulase negative staphylococci, belonging to S. capitis, S. hominis, S. haemolyticus and S. warneri, originating from the collection of the Department of Pharmaceutical Microbiology (ZMF), Medical University of Lodz, Poland, were tested for their synergistic hemolytic activity. 83% of strains produced δ-hemolysin, however, the percentage of positive strains of S. haemolyticus, ...