Acute subdural hematoma (ASDH) constitutes one of the most critical emergencies in neurosurgery and rapid spontaneous resolution of ASDH is an infrequent phenomenon. Several mechanisms have been attributed to explain this phenomenon including redistribution of subdural blood, dilution by cerebral spinal fluid and brain atrophy. Rapid resolution of ASDH related to coagulopathy is a rare phenomen...

Congenital leukemia is rarely encountered in clinical practice, even in tertiary children's hospitals. Leukemia may cause significant coagulopathy, putting the patient at risk of intracranial hemorrhage. In this case, the authors present a female infant with a unique mixed phenotypic congenital acute myeloid leukemia showing mixed-lineage leukemia (MLL) rearrangement and severe coagulopathy res...

See also Leitner JM, Jilma B, Spiel AO, Sterz F, Laggner AN, Janata KM. Massive pulmonary embolism leading to cardiac arrest is associated with consumptive coagulopathy presenting as disseminated intravascular coagulation. This issue, pp 1477–82; Thachil J. DIC score predicts mortality in massive clot coagulopathy as a result of extensive pulmonary embolism: a rebuttal. This issue, pp 1657–8; L...

Many years ago, while I was a Chief Resident in my neurological surgery training program, I solicited the aid of my Department Chairman to have the Emergency Department add coagulation testing to the routine labs acquired on head trauma patients. Believe it or not, at that time, despite knowledge that coagulopathy frequently complicates traumatic brain injury (TBI), such testing was usually not...

An 87-year-old man with an extensive past medical history was admitted for evaluation of intermittent hemoptysis of 1 month’s duration. During the hospitalization, he developed a large, subcutaneous bleed (Figure 1) after venipuncture. The patient had a known, expanding thoracic aortic aneurysm (Figures 2 and 3), and laboratory studies were consistent with an intravascular, consumptive coagulop...

PURPOSE OF REVIEW Recent therapeutic and observational studies have demonstrated improved survival with better management of haemostasis early after injury. This review delineates our current understanding of the clinical importance, aetiology and pathophysiology of acute traumatic coagulopathy (ATC). RECENT FINDINGS Trauma causes an acute disruption of the equilibrium between all components ...

Background: Tracheal intubation for general anesthesia induction can be performed via oral or nasal routes. There is a controversy about nasal route especially in children with corrected coagulopathy because of the probable stimulation for bleeding. We aimed to determine naso-pharynx bleeding in patients with corrected coagulopathy after nasotracheal intubation. Methods: This quasi-experimenta...