background: the incidence of colorectal cancer is rising in several developing countries. in the absence of integrated endoscopy and pathology databases, adenoma detection rate (adr), as a validated quality indicator of screening colonoscopy, is generally difficult to obtain in practice. we aimed to measure the correlation of polyp-related indicators with adr in order to identify the most accur...

Background and objective: Helicobacter pylori infection is one of the most common chronic bacterial infections in the world, especially in the developing countries. This bacterium is the cause of many diseases such as lymphoma, gastritis, peptic ulcers, and stomach cancer. According to recent reports, H. pylori infection can potentially increase the risk of colon cancer. The cu...

background the sitting position, rather than squatting, during defecation has been hypothesized to be a risk factor for colorectal cancer (crc). methods we conducted a case-control study to test this hypothesis. a total of 100 crc cases from two hospitals in iran and 100 control subjects, selected from the coronary care unit (ccu) of those same hospitals were selected for this study. we adminis...

curcumin exhibits both cancer- preventive activity and growth inhibitory effects on several neoplastic cells including human colon cancer. serotonin and its receptors have also been implicated in tumor development. this study investigated the effect of ritanserin, a selective serotonin 5ht2a receptor antagonist, alone and in combination with curcumin on colorectal cancer cell lines. results sho...

background: colon cancer is the third cause of cancer deaths. although colon cancer survival time has increased in recent years, the mortality rate is still high. the cox model is the most common regression model often used in medical research in survival analysis, but most of the time the effect of at least one of the independent factors changes over time, so the model cannot be used. in the c...

Background: Recent evidence suggests that regular exercise training is effective in treating various aspects of cancer. Therefore, the purpose of this study was to determine the effect of 8 weeks of aerobic interval training on monocarboxylate transporter 1 (MCT1) protein and expression of p53 gene in tumor of colon cancer mice. Methods: The present study was conducted experimentally from May ...

background: solid tumors may occur in 3% of the patients with chronic myeloid leukemia (cml). in this paper, we presented a case of cml following treatment of colon cancer. case presentation: a 25 year old man was diagnosed of adenocarcinoma of rectosigmoid treated with fluorouracil-based chemotherapy. following relapse, he received florouracil, oxaliplatin and irinotecan during the next year. ...