Objective(s): Apatinib recently has been used to treat patients with gastric cancer, but the function of apatinib in colon cancer remains unclear. This study was conducted to investigate the impacts of apatinib on the biological function and its potential mechanism of colon cancer cells in vitro. Materials and Methods:The effect of apatinib in colon cancer cells were detected by assessing cell ...

background: improvement of attitudes toward breast cancer positively affects the screening behaviors of women. imagery has been shown to have a positive impact on the screening behaviors of women. aim: this study aimed to investigate the effects of breast cancer screening training based on the systematic comprehensive health education and promotion (shep) model on the attitudes and breast self-...

BACKGROUND Understanding the age at which persistent socioeconomic inequalities in cancer survival become apparent may help motivate and support targeting of cancer site-specific interventions, and tailoring guidelines to patients at higher risk. PATIENTS AND METHODS We analysed data on more than 40,000 patients diagnosed in England with one of three common cancers in men and women, breast, c...

Background and aims: Among all cancers, colon cancer is common and deadly, yet preventable. The estimated worldwide incidence of colon cancer is more than one million new cases per year. This study was done to identify the epidemiological features and risk factors of colon cancer in different regions of Birjand. Methods: This retrospective, descriptive an...

Background and aim: Colon cancer is the third most prevalent cancer in Iran. Prolonged colon inflammation is an important factor, in the development of colon cancer. Ginger has anti-inflammatory properties due to its content of [6]-gingerol and hence can play a role in the prevention of colon cancer. In this research the effects of ginger extract on reducing expression of the C...

colorectal cancer (crc) is one of the most common forms of cancers in the world and is curable if diagnosed at the early stage. analysis of dna extracted from stool specimens is a recent advantage to cancer diagnostics. many protocols have been recommended for dna extraction from stool, and almost allof them are difficult and time consuming, dealing with high amount of toxic materials like phen...

although splenic metastasis is fairly common in disseminated cancer, solitary splenic metastasis in the absence of diffuse dissemination is rare. we report a case of 44 year-old man who developed isolated splenic metastasis of colon cancer. the patient had undergone right sided hemicolectomy for colon cancer in 1988. in 2001, he underwent reoperation because of local recurrence of tumor in the ...

BACKGROUND Spatial analyses and ecological studies are essential for epidemiology and public health. The present study combining these two methods was performed to identify spatial clusters of selected types of cancer in Japan and to determine their societal characteristics focusing on homogeneity among clusters. RESULTS Spatial clusters of high mortality rates of male colon and lung cancer a...

A search of the literature using National Library of Medicine databases and individual cancer journal articles yielded over 500 compounds with published chemopreventive activity in animals. From these, an initial 16 agents or agent combinations have been evaluated in the following animal tumor models: mouse skin papillomas/carcinomas induced by 7,12-dimethylbenz(a)anthracene/12-O-tetradecanoylp...

AIM This study is aimed to elicit the possible correlation between breast and colon cancer from molecular prospective by analyzing and comparing pathway-based biomarkers. BACKGROUND Breast and colon cancer are known to be frequent causes of morbidity and mortality in men and women around the world. There is some evidence that while the incident of breast cancer in young women is high, it is r...