in this paper, a mixed-integer linearized programming (minlp) model is presented to design a group layout (gl) of a cellular manufacturing system (cms) in a dynamic environment with considering production planning (pp) decisions. this model incorporates with an extensive coverage of important manufacturing features used in the design of cmss. there are also some features that make the presented...

molecular understanding of three-dimensional (3d) peptide: mhc models require both basic knowledge of computational modeling and skilled visual perception, which are not possessed by all students. the present model aims to simulate mhc molecular structure with the hands and make a profound impression on the students.

A computational multiscale method is proposed to simulate coupled, nonequilibrium thermomechanical processes. This multiscale framework couples together thermomechanical equations at the coarse scale with nonequilibrium molecular dynamics at the fine scale. The novel concept of distributed coarse scale thermostats enables subsets of fine scale atoms to be attached to different coarse scale node...

Preface. Our approach to cryptography is heavily based on computational complexity. Thus, some background on computational complexity is required for our discussion of cryptography. Below, we briefly recall the definitions of the complexity classes P, NP, BPP, “non-uniform P” (i.e., P/poly), and the concept of oracle machines. In addition, we discuss the type of intractability assumptions used ...

Humor plays an essential role in human interactions. Precisely what makes something funny, however, remains elusive. While research on natural language understanding has made significant advancements in recent years, there has been little direct integration of humor research with computational models of language understanding. In this paper, we propose two information-theoretic measures—ambigui...

This report provides the formalization of DEECo concepts and operational semantic of DEECo systems. Further, it establishes the refinement relation and shows the centralized tuple space semantics (as featured by local and Apache River-based knowledge providers in jDEECo). Version: March 2nd, 2013 This work was partially supported by the Grant Agency of the Czech Republic project P202/11/0312. T...

For economic reasons aircraft performance is pushed towards its physical limitations. As far as ight control is concerned, it is required to thoroughly investigate ight system dynamics, i.e., the interaction between ight dynamics (including airframe structural exibility) and ight systems (consisting of actuators/motivators and controls). Computational handling of this interaction is best taken ...

basic understanding of the process of coolant heat transfer inside an engine is an indispensable prerequisite to devise an infallible cooling strategy. coolant flow and its heat transfer affect the cooling efficiency, thermal load of heated components, and thermal efficiency of a diesel engine. an efficient approach to studying cooling system for diesel engine is a 3d computational fluid dynami...

many diseases are related to cerebrospinal .uid (csf) hydrodynamics. therefore, understanding the hydrodynamics of csf .ow and intracranial pressure is helpful for obtaining deeper knowledge of pathological processes and providing better treatments. furthermore, engineering a reliable computational method is promising approach for fabricating in vitro models which is essential for inventing gen...

despite a quite short early history, computational drug design and discovery methods can now be efficient in reducing costs and speeding up drug developing procedure. melanocortin-4 receptor (mc4r) is a g protein-coupled receptor implicated in the regulation of body weight. despite its clinical reputation, there is a lack of in-depth knowledge about structure and behavior of mc4r in lipid bilay...