psoriasis and pemphigus vulgaris are two inflammatory and autoimmune diseases. their concomitant occurrence in one patient is very rare. we describe a 57-year-old patient with a history of severe plaque type psoriasis for 2 years. after a few months, he presented with disseminated bullae and mucosal erosions which were documented as pemphigus vulgaris. both of the diseases were successfully con...

1 Department of Rheumatology and Clinical Immunology, The First Hospital of Xiamen University, Xiamen 361003, China 2Department of Biological Sciences, University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968, USA 3Microbiology, College of Medicine University of Nebraska Medical Center, Omaha, NE 68198-7660, USA 4Department of Rheumatology, Peking Union Medical College Hosp...

Systemic drugs have been used widely in the treatment of many skin diseases. Although dermatologists are familiar with the guidelines of selecting appropriate patients and prescribing systemic drugs, their knowledge about the side effects and significant interactions of systemic drugs used in dermatology is more limited. So a short review on important drug interactions seems to be useful. Some ...

Over recent decades, the development and consumption of functional probiotic foods has been increasing alongside awareness of their beneficial effects in promoting gut health as well as in disease prevention and therapy, and this has raised interest in health-promoting foods. Major probiotic mechanisms of action include enhancement of the epithelial barrier, increased adhesion to intestinal muc...

Systemic drugs are used in the treatment of several skin diseases. In order to obtain best therapeutic results and prevent side effects, the patients should be carefully screened before and thoroughly evaluated during treatment. In this article guidelines for selection and follow up of patients receiving systemic drugs for their skin diseases are presented. These drugs include azathioprine, ant...

Acquired perforating dermatosis (APD) is an uncommon disease characterized by lesions exhibiting transepidermal elimination of collagen or elastic fibers. APD affects adults and is associated with systemic diseases, mainly diabetes mellitus and renal failure. We present 8 cases of APD. Seven patients had concomitant diabetes mellitus with or without chronic renal failure, and 1 had alcoholic ci...

Fungi have long been known to affect human well being in various ways, including disease of essential crop plants, decay of stored foods with possible concomitant production of mycotoxins, superficial and systemic infection of human tissues, and disease associated with immune stimulation such as hypersensitivity pneumonitis and toxic pneumonitis. The spores of a large number of important fungi ...