The number of configurations of a polymer is reduced in the presence of a barrier or an obstacle. The resulting loss of entropy adds a repulsive component to other forces generated by interaction potentials. When the obstructions are scale invariant shapes (such as cones, wedges, lines, or planes) the only relevant length scales are the polymer size R(0) and characteristic separations, severely...

A stable nanoscale thermal hot spot, with temperature approaching 100 °C, is shown to be sustained by localized Ohmic heating of a focused electric field at the tip of a slender conic nanopore. The self-similar (length-independent) conic geometry allows us to match the singular heat source at the tip to the singular radial heat loss from the slender cone to obtain a self-similar steady temperat...

We developed a modified paper spray ionization (PSI) platform, named as paper cone spray ionization (PCSI), for direct mass spectrometric analysis of raw solid samples. The major modification from conventional PSI was the geometry of the paper base: PCSI uses a triangular-pyramidal-shaped paper tip instead of a planar triangular-shaped one. This three-dimensional paper cone serves as a sample c...

A stochastic, nonlinear dynamic model is proposed to explain the growth cone at the tip of a cell process, such as a growing axon or dendrite of a neuron. The model explains the outward motion of the tip as an extension of the cytoskeleton, using the actin-myosin system as a molecular motor. The kinetic energy is supplied by heat from ATP hydrolysis in the form of random motion of water molecul...

Solution is developed for the build!up\ steady and post!arrest dissipative pore ~uid pressure _elds that develop around a conical penetrometer advanced in a poroelastic medium[ The analog with cone penetrometer testing is direct\ and is used to enable continuous distributions of permeability and di}usivity to be determined\ with depth[ Solution for a point normal dislocation migrating in a poro...

A drop of water deposited on a cold plate freezes into an ice drop with a pointy tip. While this phenomenon clearly finds its origin in the expansion of water upon freezing, a quantitative description of the tip singularity has remained elusive. Here we demonstrate how the geometry of the freezing front, determined by heat transfer considerations, is crucial for the tip formation. We perform sy...

This study adopts Multivariate Adaptive Regression Spline (MARS) and Least Square Support Vector Machine (LSSVM) for prediction of undrained shear strength (su ) of clay, based Cone Penetration Test (CPT) data. Corrected cone resistance (qt ), vertical total stress (σv ), hydrostatic pore pressure (u0 ), pore water pressure at the cone tip (u1 ), and pore water pressure just above the cone base...

The produced electric and magnetic fields due to lightning strikes to mountainous ground are determined in this paper. For the sake of simplicity a cone-shaped ground with finite conductivity is assumed to represent a natural nonflat ground. By this assumption, we deal with an axillary symmetrical structure so we use the cylindrical 2D-FDTD to save the simulation memory and time, dramatically. ...

Pollen tube growth is a polarized growth process whereby the tip-growing tubes elongate within the female reproductive tissues to deliver sperm cells to the ovules for fertilization. Efficient and regulated membrane trafficking activity incorporates membrane and deposits cell wall molecules at the tube apex and is believed to underlie rapid and focused growth at the pollen tube tip. Rab GTPases...

The intraaxonal distribution of labeled glycoproteins in the regenerating hypoglossal nerve of the rabbit was studied by use of quantitative electron microscope autoradiography. 9 d after nerve crush, glycoproteins were labeled by the administration of [3H]fucose to the medulla. The distribution of transported 3H-labeled glycoproteins was determined 18 h later in segments of the regenerating ne...