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Previous studies have revealed the aberrant expression of a number of microRNAs (miRNA/miRs) in the blood circulation of patients with breast cancer (BC). The aim of the present study was to assess the effect of neoadjuvant chemotherapy on the levels of a panel of BC-associated miRNAs, which are at relatively low (let-7, miR-10b, miR-34, miR-155, miR-200c and miR-205) or abundant (miR-21, miR-1...
The e!ects of positive and negative correlation, c, between (N"100) random synaptic inputs (each "ring at 100 Hz) on the mean and coe$cient of variation (CV) of interspike interval (ISI) of the Hodgkin}Huxley model are examined, for di!erent IPSP/EPSP frequency ratios, r. Mean (ISI) and CV are approximately constant (30}40 ms, and 0.75, respectively) under independence for r3[0,1], unlike the l...
Epidemiological data about pelvic fractures are limited. Until today, most studies only analyzed inpatient data. The purpose of this study was to estimate incidence rates of pelvic fractures in the German population aged 60 years or older, based on outpatient and inpatient data. We conducted a retrospective population-based observational study based on routine data from a large health insurance...
Superalkali Li3 dissolved in gaseous ammonia is investigated by density functional theory. Similar to the lithium atom, Li3 can coordinate up to four ammonia molecules. Among the structural isomers of Li3(NH3)n (n = 1-4), the one with separately distributed NH3 ligands is preferred. Most of the Li3(NH3)n species possess the alkalide characteristics and exhibit considerably large static first hy...
The degeneration of articular cartilage results from osteoarthritis and many other forms of severe arthritis. Current treatments for cartilage repair are less than satisfactory, and rarely restore a full function or return the tissue to its natural state. The leading strategies in the treatment are aimed at the transplantation of cells and/or the use of various biological grafts, bioactive agen...
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