Abstract Chemical gardens, which are self‐organizing, abiotic, inorganic precipitates in far‐from‐equilibrium systems, of interest for prebiotic chemistry/origin life research and, under certain reaction can be considered hydrothermal vent analogs. While the presence different additives to chemical including phosphate and amino acids, have been explored, reactivity organic molecules garden syst...

Oligonucleotide microarray fabrication by chemical synthesis using photoacid generators in solid films could have advantages over existing methods, but has not matched the accuracy of conventional synthesis where detritylation is performed with acid solutions. To address this problem, we explored the kinetics and equilibria of nucleoside detritylation in solid films, using trichloroacetic acid ...

ibuprofen solid dispersions were prepared by the solvent and fusion-solvent methods using polyethylene glycol (peg), polyvinylpyrrolidone (pvp), eudragit rs po, eudragit rl po and hydroxypropylmethylcellulose (hpmc) as carriers to improve physicochemical characteristics of ibuprofen. the prepared solid dispersions were evaluated for the flowability, solubility characteristics and dissolution be...

Meloxicam is a poorly water soluble non steroidal anti-inflammatory drug and antipyretic agent. The aim of the present work was to investigate the effect of different types of carriers on in vitro dissolution of meloxicam. Meloxicam solid dispersions were prepared by physical mixing, co-grinding and solvent evaporation methods with polyethylene glycol (PEG) 6000. The effect of solubilization by...

Silica sulfuric acid is employed as solid acid catalyst for the clean and less hazardousprotection of carbonyl compounds as 2,4-dinitrophenylhydrazone under solvent-free conditions.

Purpose: Following the discovery of the carcinogenicity of phenolphthalein and the subsequent ban of this compound in several countries this study was undertaken to develop compounded formulations of laxative products containing the stimulant laxatives sennosides A and B. Methods: DSC and HPLC analysis was used to determine the compatibility of sennosides with commonly used excipients before co...

Each of 22 isolates of Candida albicans was induced to produce aerial hyphae by culturing on a solid medium containing a peptone, acid-hydrolyzed casein, soluble starch, and agar in an atmosphere of 10% CO(2) at 37 C and room temperatures. Production of aerial hyphae is not diagnostic for C. albicans. Some of the other species of Candida may also produce such structures.

A universal label-free method for the spectroscopic investigation of polyhistidine-tagged proteins is presented. A solid supported lipid bilayer (SSLB, picture) containing nitrilotriacetic-acid-modified lipids is attached on top of a germanium attenuated total reflection crystal by hydrophilic interactions. Any His tag-modified protein can be immobilized and investigated by FTIR spectroscopy.

effect of sucrose replacement with date syrup powder on physiochemical properties of sponge cake such as specific gravity, volume, apparent density, solid density, porosity, symmetry, moisture content, water activity, crust color and textural firmness was studied. batter specific gravity of the control sample was higher than that of other samples. sucrose replacement with 100% of date syrup pow...

The synthesis of the lipophilic chiral amino acid 1 bearing the bicyclo[1.1.1]pentane moiety is described. Linear and cyclic hexapeptides of the type Arg-Arg-Xaa-Yaa-Arg-Phe containing 1 instead of one or two tryptophan residues are prepared by solid phase peptide synthesis and the antimicrobial and hemolytic activity of the peptides obtained are discussed.