BACKGROUND Members of the predatory gastropod genus Conus use a venom comprised of a cocktail of peptide neurotoxins, termed conotoxins or conopeptides, to paralyze prey and conotoxin gene family members diversify via strong positive selection. Because Conus venoms are used primarily to subdue prey, the evolution of venoms is likely affected by predator-prey interactions. METHODOLOGY/PRINCIPA...

Acid-sensing ion channels (ASICs) are proton-gated Na+ channels that are expressed throughout the nervous system. ASICs have been implicated in several neuronal disorders, like ischemic stroke, neuronal inflammation, and pathological pain. Several toxins from venomous animals have been identified that target ASICs with high specificity and potency. These toxins are extremely useful in providing...

3D textile model plays an important role in textile engineering. However, not much work focus on high-quality 3D textile reconstruction. The texture is also limited by photography methods in 3D scanning. This paper presents a novel framework of reconstructing a high-quality 3D textile model with a synthesized texture. Firstly, a pipeline of 3D textile processing is proposed to obtain a better 3...

Disulfide-rich peptide venoms from animals such as snakes, spiders, scorpions, and certain marine snails represent one of nature's great diversity libraries of bioactive molecules. The various species of marine cone shells have alone been estimated to produce >50,000 distinct peptide venoms. These peptides have stimulated considerable interest because of their ability to potently alter the func...

The use of nanotechnology in the textile industry has increased rapidly due to its unique and valuable properties. The present status of nanotechnology use in textiles is reviewed, with an emphasis on improving various properties of textiles.

Figure 1 Lumbar sagittal T2-weighted (A) and post-contrast fat-suppressed T1-weighted (B) imaging shows a heterogeneous intradural mass within the conus medullaris, with a central bright signal on T2-WI and lack of contrast enhancement. Note, at the same T12—L1 level, the herniated disc that is contiguous with the mass. Figure 1 Coupes sagittales pondérées en T2 (A) et en T1 après pidermoid-cys...

The recent challenge in textile supply chain management is the development of collaboration network which accommodates diverse concerns of various participants while explicitly recognizing interdependencies and promoting effective relationship management. This study is designed to suggest a collaboration network model for textile industry and apply it to establish a desirable framework for the ...

Specialized predators on polychaetes, fishes, hemichordates or other molluscs, members of the predominantly tropical gastropod genus Conus diversified rapidly during the Miocene to constitute the most species-rich modern marine genus. We used DNA sequence data from mitochondrial and nuclear loci of 76 Conus species to generate species-level phylogenetic hypotheses for this genus and then mapped...

For the understanding of the developmental significance of various parts of the normal ventricular septum, 54 normal human embryos and 154 mature heart specimens showing different types of VSD’s and AV canal malformation were studied. The pars interventriculare of the septum membranaceum is derived primarily from the right superior and inferior tubercies of the AV cushions. The pars atrioventri...