A progressive, apparently inherited corneal dystrophy is described in an inbred line of Manx cats. Initial changes in the cornea are seen at four months of age and characterized by anterior stromal edema. Progressive worsening of the condition produces severe bullous keratopathy with eventual breakdown of both epithelium and stroma. Light microscopic and ultrastructural studies in the advanced ...

To report a novel mutation within the CHST6 gene, as well as describe light and electron microscopic features of a case of macular corneal dystrophy. A 59-year old woman with macular corneal dystrophy in both eyes who had decreased visual acuity underwent penetrating keratoplasty. Further studies including light and electron microscopy, as well as DNA analysis were performed. Light microscopy o...

An interest in the possibility of a systemic lipid disturbance in Schnyder's corneal dystrophy stems from the work of Bonnet, Paufique, and Bonamour (I934), who first suggested that the needle-shaped corneal deposits in this condition consisted of cholesterol. The present study is of great interest since it describes a family in which Schnyder's central crystalline stromal dystrophy coexisted w...

Histochemical evidence suggests that the amorphous stromal deposits of corneal granular dystrophy are composed essentially of a non-collagenous protein or polypeptide complex, the precise nature of which, however, is unknown (Seitz and Goslar, I963; Garner, I969). Electron microscopy fortunately enables a further dimension of this material to be studied, and the present report gives the finding...

OBJECTIVE The aim was to compare the corneal topography and tomography parameters of macular corneal dystrophy (MCD), granular corneal dystrophy (GCD) and lattice corneal dystrophy (LCD) patients obtained by Scheimpflug imaging system. METHODS The charts, photographs and topography images of patients were reviewed retrospectively. This study included 73 eyes of 73 patients (28 MCD, 20 GCG and...

Four eyes of 2 patients with corneal edema due to Fuchs' endothelial dystrophy were treated with CXL using the standard protocol. Since no improvement in visual acuity, corneal clarity, thickness, or pain sensation was evident in any eye at month 12, 2 eyes of the 2 patients were retreated, this time, following intraoperative corneal dehydration with glycerol 70% drops. This retreatment also fa...

Keratosis follicularis spinulosa decalvans (KFSD) is a rare X linked disease which is characterised by follicular hyperkeratosis of the skin and corneal dystrophy. Seven male patients and six female carriers are described. Special attention has been paid to the dermatological and ophthalmic markers of KFSD in patients and carriers. The most prominent features present in the male patients were f...

BACKGROUND Unilateral lattice corneal dystrophy is a rare entity. OBJECTIVE To highlight the evidence of unilateral lattice corneal dystrophy in a young female. CASE A young 28 years old female presented to the outpatient department of Ophthalmology with slowly progressive diminution of vision in left eye for one month. On ophthalmological examination best corrected visual acuity (BCVA) was...