AIMS To report the histological findings in two AlphaCor artificial corneas explanted following complications,to compare the mechanism of biointegration and/or failure of the device and the correlation with clinical histories. METHODS The first patient was diagnosed with optic deposits and corneal melting during the late postoperative period and required the removal of the device. The second ...

normal 0 false false false en-us x-none ar-sa background : the aim of this study was to determine the correlation between corneal hysteresis (ch) and the corneal resistance factor (crf), which are both novel methods of analyzing ocular rigidity/elasticity, and various corneal characteristics, mainly corneal volume in normal subjects. methods : this cross-sectional study included 500 normal eyes...

Introduction: Ulcerative keratitis is a common condition in horses due to their large, prominent eyes and can be potentially sight limiting if not diagnosed early and treated properly. Superficial, non-infected ulcers commonly heal rapidly; whereas stromal degradation associated with infected ulcers can rapidly progress to perforation of the cornea. This is characterized by increased proteolyti...

Changes in corneal architecture with the application of controlled heat have been shown to be clinically useful and well tolerated. A fine hypodermic microthermistor was utilized to record the temperature at both superficial and deep levels of the rabbit cornea after the application of the thermokeratoplasty (TKP) probe at 90° C. or 130° C. These temperature readings revealed that the known cor...

PURPOSE A fish scale-derived collagen matrix (FSCM) is proposed as an alternative for human donor corneal tissue. Light scatter and light transmission of the FSCM were measured and compared with human cornea, and its short-term biocompatibility was tested in a rat model. METHODS light scatter was determined with a straylight measuring device, whereas light transmission was measured using a br...

Purpose We report a rare case of Phialemonium obovatum fungal keratitis in a patient sustaining a corneal laceration from impact with a piece of moldy plaster. Observations The patient was treated with topical voriconazole with resolution of active keratitis and formation of a stromal scar. The patient's final visual acuity was 20/20 in the affected eye. Conclusions and importance There is ...

We describe a rare case of an infant who was born with multiple congenital anomalies, including the absence of eyelids. This patient had many dysmorphic features consistent with a severe phenotype of ablepharon-macrostomia syndrome (AMS) including a fish-like appearance of the mouth, rudimentary ears, absence of body hair, thin skin, absent nipples, abdominal distension, and genital abnormaliti...

PURPOSE To compare the histopathology of three PMMA collar button type keratoprosthesis (KPro)/corneal specimens, explanted due to various complications, with that from one KPro/corneal specimen taken postmortem from an otherwise "healthy" enucleated eye. METHODS Patient 1 (chemical injury) had no problems for 3 years after KPro placement; the entire eye was obtained postmortem. Patient 2 (re...