we aimed to develop a cost-effective and robust method to predict drug resistance in individualpatients. representative tissue fragments were obtained from tumors removed from femalepatients, aged 24-74 years old. the tumor tissue was taken by a histopathology’s or a surgeonunder sterile conditions. cells obtained by enzymatic dissociation from tumor after surgery, werecultured as a monolayer f...

pluronic based nano-particulate systems are innovative platforms for delivery of anti-cancer agents. these systems due to their pharmacological properties and suitable physicochemical characteristics are great opportunity for development cancer therapeutics. this mini-review tries to provide a more detailed overview on the currently available pluronic based drug delivery systems. in the section...

Advances in early detection, prevention, and treatment have resulted in consistently falling cancer death rates in the United States. In parallel with these advances have come significant increases in the cost of cancer care. It is well established that the cost of health care (including cancer care) in the United States is growing more rapidly than the overall economy. In part, this is a resul...

cancer patients are more susceptible to adverse drug-drug interactions (ddis) due to receiving multiple medications especially chemotherapy medications, hormonal agents and supportive care drugs. the aim of this study is to describe the prevalence of potential ddis and to identify risk factors for these potential interactions in hospitalized cancer patients in a developing country.a cross-secti...

In 2014, the IMS Institute for Healthcare Informatics estimated that, by 2018, global spending on medicines would increase to almost $1.3tr (£900bn; €1.2tr), an increase of over 30% over five years. Forty per cent of this growth is expected to come from specialty drugs such as cancer drugs and immunosuppressants, with predictions that by 2018, such drugs will account for 50% of drug spending in...

The healthcare burden of cancer Cancer places a signifi cant, and growing, burden on healthcare systems around the world. Improved therapies and changing demographics are conspiring to increase the already considerable drain on resources. On the one hand, population growth and ageing will increase the number of new cancer cases in the coming years [1]; on the other, advances in diagnosis and ma...

Background The NHS Cancer Drugs Fund (CDF) was established in 2010 to reduce delays and improve access to cancer drugs, including those that had been previously appraised but not approved by NICE (National Institute for Health and Care Excellence). After 1.3 billion GBP expenditure, a UK parliamentary review in 2016 rationalized the CDF back into NICE. Methods This paper analyses the potentia...

background : chemotherapy is an important treatment for cancer, yet some of its side effects are serious and painful. many patients with cancer suffer from psychiatric disorders that most likely result from therapeutic drugs or mental strategies to cope with their illness. progressive muscle relaxation is one of the cost effective, self-help methods that promotes mental health in healthy partic...

    Background: Colorectal cancer is one of the most common cancers in Iran. However little is known about the economic burden associated with this cancer in Iran. The aim of this study was to estimate the economic burden of colorectal cancer in Iran in the year 2012.    Methods: We used the prevalence-based approach and estimated direct and indirect costs of all color...

It sometimes feels as though the frequency of “healthcare scandals” is increasing. The veil is lifted, and the public gets disturbing new insight into healthcare’s harsher realities. The Mid Staffordshire scandal was a notable example; the US opioid crisis a more recent one. Last month, what might be termed a “cancer drugs scandal” hit the headlines. The trigger was a package of articles in The...