Engineering craniofacial bone tissues is challenging due to their complex structures. Current standard autografts and allografts have many drawbacks for craniofacial bone tissue reconstruction; including donor site morbidity and the ability to reinstate the aesthetic characteristics of the host tissue. To overcome these problems; tissue engineering and regenerative medicine strategies have been...

(1) Hospital for Rehabilitation of Craniofacial Anomalies at University of São Paulo – HRAC-USP, Bauru, São Paulo, Brazil. (2) Hospital for Rehabilitation of Craniofacial Anomalies at University of São Paulo – HRAC-USP, Bauru, São Paulo, Brazil. (3) Speech Language Department at Bauru School of Dentistry, University of São Paulo FOB-USP and Laboratory of Physiology of the Hospital for Rehabilit...

Obstructive sleep apnoea (OSA) is due to craniofacial changes and acromegaly. The question addressed by this study was whether growth hormone (GH) induced craniofacial changes might explain persisting OSA despite endocrine inactivity in acromegaly. Nineteen patients treated for acromegaly were examined cephalometrically for craniofacial changes and polysomnographically for OSA. Twelve patients ...

Craniofacial clefts have an incidence of 1/700 [...]

Forensic artists use tissue thicknesses at well known landmarks on the craniofacial skeleton to generate a potential likeness of an individual from a skull. This is a very subjective and time consuming process. We present two prototype software packages: one for simulating the growth of a craniofacial skeleton either forwards or backwards in time, and the other for generating a facial reconstru...

BACKGROUND Citation analysis is a recognized scientometric method of classifying cited articles according to the frequency of which they have been referenced. The total number of citations an article receives is considered to reflect it's significance among it's peers. METHODS Until now, a bibliometric analysis has never been performed in the specialty of craniofacial anomalies and craniofaci...

The quantification, analysis, prediction and simulation of the growth of the craniofacial complex is discussed in the context of a two-dimensional coordinate model of craniofacial morphology. Data accumulated from lateral X-ray films (cephalograms) are used, in conjunction with the model, to describe and analyze craniofacial growth; to predict the future size of craniofacial structures, the fut...

Synchondrosis is defined as the development of a union between two bones by the formation of either hyaline cartilage or fibro-cartilage. This paper reviews the relationship between cranial base synchondroses and craniofacial development. The cranial base synchondroses are important growth centers of the craniofacial skeleton. Their abnormalities lead to numerous growth and developmental condit...

The term craniofacial anomalies literally encompasses all congenital deformities of the cranium and face. More specifically, however, the term has come to imply congenital deformities of the head that interfere with physical and mental well-being (Marsh and Vannier, 1985). There are practically no epidemiological studies of craniofacial malformations as such. Myrianthopoulos (1982) reviewed dat...

Objective: Silybum marianum has been used for centuries in herbal medicine for treatment of liver diseases. Currently, there is no data available on the possible effects of silymarin on fetal development. This study aimed to investigate the teratogenic effect of silymarin on BALB/c mice fetuses. Materials and Methods: A total of 40 pregnant mice were divided into 4 groups of 10 mice each. Three...