•Unified solution to decarboxylative cross-nucleophile coupling reactions•Photoactive Fe(III) carboxylates + Fe(III)-mediated oxidation•Fe(III) salts are non-toxic, earth abundant, and low cost•Direct formation of C–C, C–O, C–S, C–N bonds without prefunctionalization Carboxylic acids valuable chemical building blocks because they widely available with significant structural diversity. Decarboxy...